Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin
Research output: Contribution to journal › Journal article › Research › peer-review
Gavin Carr, Michael Poulsen, Jonathan L. Klassen, Yanpeng Hou, Thomas P. Wyche, Tim S. Bugni, Cameron R. Currie, Jon Clardy
Microtermolides A (1) and B (2) were isolated from a Streptomyces sp. strain associated with fungus-growing termites. The structures of 1 and 2 were determined by 1D- and 2D-NMR spectroscopy and high-resolution mass spectrometry. Structural elucidation of 1 led to the re-examination of the structure originally proposed for vinylamycin (3). Based on a comparison of predicted and experimental (1)H and (13)C NMR chemical shifts, we propose that vinylamycin's structure be revised from 3 to 4.
|Number of pages||4|
|Publication status||Published - 2012|