Human trichuriasis: whipworm genetics, phylogeny, transmission and future research directions

Publikation: Bidrag til tidsskriftTidsskriftartikel

Martha Betson, Martin Jensen Søe, Peter Nejsum

Human trichuriasis is a neglected tropical disease which affects hundreds of millions of people worldwide and is particularly prevalent among children living in areas where sanitation is poor. This review examines the current knowledge on the taxonomy, genetics and phylogeography of human Trichuris and its relationship to whipworm parasites in other host species. The evidence for zoonotic transmission of Trichuris and the emergence of anthelmintic resistance is assessed. In addition, the implications of the recent publication of the genomes and transcriptomes of multiple Trichuris species are discussed. Finally, priorities for future research in Trichuris genetics are proposed.
OriginalsprogEngelsk
TidsskriftCurrent Tropical Medicine Reports
Vol/bind2
Udgave nummer4
Sider (fra-til)209-217
Antal sider9
DOI
StatusUdgivet - 2015

ID: 144740194