Survival and characteristics of pediatric salivary gland cancer: A systematic review and meta-analysis

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Martin Zamani, Christian Grønhøj, Jakob Schmidt Jensen, Christian von Buchwald, Birgitte Wittenborg Charabi, Thomas Hjuler

A systematic search of PubMed, EMBASE, and the Cochrane Library for studies from 2000 to 2017 including children aged 0-19 with salivary gland cancer was performed. In 19 studies, 749 children (median age of 14.2 years, female to male ratio of 1.4:1) were included; 72% had parotid tumors and 95% underwent surgery, of whom 65% had surgery alone and 24% with adjuvant radiotherapy. Low-grade and stage mucoepidermoid carcinoma were the most frequent cancer. The 5-year overall- and disease-free survival was 94% and 83%. Recurrence was observed in 20% at a median of 1.1 years from diagnosis.

OriginalsprogEngelsk
Artikelnummere27543
TidsskriftPediatric Blood & Cancer
Vol/bind66
Udgave nummer3
Antal sider8
ISSN1545-5009
DOI
StatusUdgivet - 2019

Bibliografisk note

© 2018 Wiley Periodicals, Inc.

ID: 224551809