Premotor cortex modulates somatosensory cortex during voluntary movements without proprioceptive feedback

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Mark Schram Christensen, Jesper Lundbye-Jensen, Svend Sparre Geertsen, Tue Hvass Petersen, Olaf B Paulson, Jens Bo Nielsen

Movement perception relies on sensory feedback, but the involvement of efference copies remains unclear. We investigated movements without proprioceptive feedback using ischemic nerve block during fMRI in healthy humans, and found preserved activation of the primary somatosensory cortex. This activation was associated with increased interaction with premotor cortex during voluntary movements, which demonstrates that perception of movements relies in part on predictions of sensory consequences of voluntary movements that are mediated by the premotor cortex.
OriginalsprogEngelsk
TidsskriftNature Neuroscience
Vol/bind10
Udgave nummer4
Sider (fra-til)417-9
Antal sider3
ISSN1097-6256
DOI
StatusUdgivet - 1 apr. 2007

Bibliografisk note

CURIS 2007 5200 026

ID: 882321