Mulig terapeutisk intervention med haemmere og fremmere af fosfolipase A 2 -subtyper

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Miriam Kolko, Chen Zhan, Jens Rovelt Andreasen, Jan Ulrik Prause, Steffen Heegaard, Miriam Kolko

Phospholipase A2 (PLA2) is a group of enzymes discovered more than a century ago in insect and snake poison. Not more than 20 years ago they were identified in vertebrates, and during the last five years, research has accelerated in relation to isolating and cloning several members of this super-family in humans. PLA2 inhibitors are in the process of being developed for pharmaceutical use. The purpose of this review is to outline the relevance and prospectives of PLA2 in a clinical perspective.

TidsskriftUgeskrift for Laeger
Udgave nummer2
Sider (fra-til)115-9
Antal sider5
StatusUdgivet - 8 jan. 2007


  • Brain Diseases, Cardiovascular Diseases, Enzyme Inhibitors, Humans, Inflammation, Neoplasms, Phospholipases A, Phospholipases A2

ID: 128614884