Genomic evidence for the Pleistocene and recent population history of Native Americans

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Maanasa Raghavan, Matthias Steinrücken, Kelley Harris, Stephan Schiffels, Simon Rasmussen, Michael DeGiorgio, Anders Albrechtsen, Cristina E. Valdiosera Morales, Maria del Carmen Avila Arcos, Anna Sapfo Malaspinas, Anders Eriksson, Ida Moltke, Mait Metspalu, Julian R Homburger, Jeff Wall, Omar E Cornejo, José Victor Moreno Mayar, Thorfinn Sand Korneliussen, Tracey Lynn Pierre, Morten Rasmussen & 81 andre Paula Campos, Peter de Barros Damgaard, Morten Erik Allentoft, John Lindo, Ene Metspalu, Ricardo Rodríguez-Varela, Josefina Mansilla, Celeste Henrickson, Andaine Seguin-Orlando, Helena Malmström, Thomas Stafford jr., Suyash S Shringarpure, Andrés Moreno-Estrada, Monika Karmin, Kristiina Tambets, Anders Bergström, Yali Xue, Vera Warmuth, Andrew D Friend, Joy Singarayer, Paul Valdes, Francois Balloux, Ilán Leboreiro, Jose Luis Vera, Hector Rangel-Villalobos, Davide Pettener, Donata Luiselli, Loren G Davis, Evelyne Heyer, Christoph P E Zollikofer, Marcia S Ponce de León, Colin I Smith, Vaughan Grimes, Kelly-Anne Pike, Michael Deal, Benjamin T Fuller, Bernardo Arriaza, Vivien Standen, Maria F Luz, Francois Ricaut, Niede Guidon, Ludmila Osipova, Mikhail I Voevoda, Olga L Posukh, Oleg Balanovsky, Maria Lavryashina, Yuri Bogunov, Elza Khusnutdinova, Marina Gubina, Elena Balanovska, Sardana Fedorova, Sergey Litvinov, Boris Malyarchuk, Miroslava Derenko, M J Mosher, David Archer, Jerome Cybulski, Barbara Petzelt, Joycelynn Mitchell, Rosita Worl, Paul J Norman, Peter Parham, Brian M Kemp, Toomas Kivisild, Chris Tyler-Smith, Manjinder S Sandhu, Michael Crawford, Richard Villems, David Glenn Smith, Michael R Waters, Ted Goebel, John R Johnson, Ripan S Malhi, Mattias Jakobsson, David J. Meltzer, Andrea Manica, Richard Durbin, Carlos D Bustamante, Yun S Song, Rasmus Nielsen, Eske Willerslev

How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.

OriginalsprogEngelsk
Artikelnummer6250
TidsskriftScience (New York, N.Y.)
Vol/bind349
Udgave nummer6250
ISSN0036-8075
DOI
StatusUdgivet - 2015

    Forskningsområder

  • Americas, Gene Flow, Genomics, History, Ancient, Human Migration, Humans, Indians, North American, Models, Genetic, Siberia

ID: 145241214