Forskningsområder

  1. Udgivet

    Phorbol Rearrangements. / Zimmermann, Tomas; Franzyk, Henrik; Christensen, Søren Brøgger.

    I: Journal of Natural Products, Bind 81, Nr. 9, 15.09.2018, s. 2134-2137.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  2. Udgivet

    Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis. / Zimmermann, Tomas; Christensen, Søren Brøgger; Franzyk, Henrik.

    I: Molecules, Bind 23, Nr. 6, 1463, 15.06.2018.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  3. Udgivet

    Urban Displacement and Resettlement in Zimbabwe: The Paradoxes of Propertied Citizenship. / Hammar, Amanda.

    I: African Studies Review, 12.2017.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  4. Udgivet

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+-Transport ATPase (SPCA1a). / Jialin, Chen; de Raeymaecker, Joren ; Hovgaard, Jannik Brøndsted; Smaardijk, Susanne; Vandecaetsbeek, Ilse; Wuytack, Frank; Møller, Jesper Vuust; Eggermont, Jan; de Meyer, Marc; Christensen, Søren Brøgger; Vangheluwe, Peter.

    I: Journal of Biological Chemistry, Bind 292, Nr. 17, 2017, s. 6938-6951.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  5. Udgivet

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. / Krall, Jacob; Jensen, Claus Hatt; Bavo, Francesco; Falk-Petersen, Christina Birkedahl; Haugaard, Anne Stæhr; Vogensen, Stine Byskov; Tian, Yongsong; Nittegaard-Nielsen, Mia; Sigurdardóttir, Sara Björk; Kehler, Jan; Kongstad, Kenneth Thermann; Gloriam, David E.; Clausen, Rasmus Prætorius; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    I: Journal of Medicinal Chemistry, Bind 60, Nr. 21, 2017, s. 9022-9039.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  6. Udgivet

    Lithostratigraphy, geology and geochemisttry of the volcanic rocks of the Vaigat Formation on Disko and Nuussuaq, Paleocene of West Greenland. / Pedersen, Asger Ken; Larsen, Lotte Melchior; Pedersen, Gunver Krarup .

    Copenhagen : The Geological Survey of Denmark and Greenland, 2017. 244 s. (Geological Survey of Denmark and Greenland Bulletin, Bind 39).

    Publikation: Bog/antologi/afhandling/rapportBogForskningfagfællebedømt

  7. Udgivet

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation. / Jensen, Christina Mernøe; Chow, Hsiao-Qing; Chen, Ming; Zhai, Lin; Frydenvang, Karla Andrea; Liu, Huizhen ; Franzyk, Henrik; Christensen, Søren Brøgger.

    I: European Journal of Medicinal Chemistry, Bind 114, 2016, s. 118-133.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  8. Udgivet

    Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection. / Mertz, Nina; Larsen, Susan Weng; Larsen, Claus Selch.

    2016. Poster session præsenteret ved 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, Storbritannien.

    Publikation: KonferencebidragPosterForskningfagfællebedømt

  9. Udgivet

    Cytochrome P450 Mediated Drug Metabolism. / Olsen, Lars; Jørgensen, Flemming Steen; Oostenbrink, Chris.

    New Horizons in Predictive Drug Metabolism and Pharmacokinetics. red. / Alan G.E. Wilson. Cambridge : Royal Society of Chemistry, 2016. s. 66-78 (RSC Drug Discovery, Bind 49).

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningfagfællebedømt

  10. Udgivet

    The potential of protein-nanomaterial interaction for advanced drug delivery. / Peng, Qiang; Mu, Huiling.

    I: Journal of Controlled Release, Bind 225, 23.01.2016, s. 121-132.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  11. Udgivet

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats. / Berthelsen, Ragna; Holm, Rene; Jacobsen, Jette; Kristensen, Jakob; Abrahamsson, Bertil; Müllertz, Anette.

    I: Molecular Pharmaceutics, Bind 12, Nr. 4, 06.04.2015, s. 1062-1071.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  12. Udgivet

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development. / Doan, Thi Quynh Nhu; Christensen, Søren Brøgger.

    I: Current Pharmaceutical Design, Bind 21, Nr. 38, 10.2015, s. 5505-5517.

    Publikation: Bidrag til tidsskriftReview

  13. Udgivet

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score. / Laustsen, Andreas Hougaard; Lohse, Brian.

    I: Toxicon, Bind 104, 15.09.2015, s. 43-45.

    Publikation: Bidrag til tidsskriftLetter

  14. Udgivet

    Noter til Organisk Kemi for Biovidenskab : Organisk og bioorganisk kemi 2015. / Nielsen, John.

    25 s. 2015, .

    Publikation: AndetAndet bidragUndervisning

  15. Udgivet

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice. / Diep, Thi Ai; Golbas, Golfam; Hansen, Harald S.

    2014.

    Publikation: KonferencebidragKonferenceabstrakt til konferenceForskning

  16. Udgivet

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking. / Hauser, Alexander Sebastian.

    I: Medicinal Chemistry Research, Bind 23, Nr. 8, 01.08.2014, s. 3861.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  17. Udgivet

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Brandt, Asbjørn; Halling-Sørensen, Bent; Björklund, Erland.

    I: International Journal of Environmental Analytical Chemistry, Bind 93, Nr. 14, 25.02.2013, s. 1500-1512.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  18. Udgivet

    Altered anziety/depression-like behaviours in mice deficient in tetrahydrobiopterin. / Nasser, Arafat; Birk Møller, Lisbeth; Andreasen T., Jesper.

    2013.

    Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningfagfællebedømt

  19. Udgivet

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation. / Outzen, Emilie Middelbo; Mehryar, Rahila; Boonen, Harrie C.M.; Nielsen, Anette Sams; Sheykhzade, Majid.

    2013. Poster session præsenteret ved DRA Summer School 2013, Copenhagen, Danmark.

    Publikation: KonferencebidragPosterForskning

  20. Udgivet

    Lactate dehydrogenase assay for assessment of polycation cytotoxicity. / Parhamifar, Ladan; Andersen, Helene; Moghimi, Seyed Moien.

    Nanotechnology for Nucleic Acid Delivery. Bind 948 2013. s. 13-22 (Methods in Molecular Biology).

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskning

  21. Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    I: Pharmaceutical Research, Bind 30, Nr. 1, 01.2013, s. 280-289.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  22. Udgivet

    Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    I: Pharmaceutical Research, Bind 30, Nr. 1, 2013, s. 280-289.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  23. Udgivet

    Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain. / Rodríguez-Navas, Carlos ; Björklund, Erland; Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Maya, Fernando; Forteza, Rafael; Cerdà, Víctor.

    I: Archives of Environmental Contamination and Toxicology, Bind 61, Nr. 1, 2013, s. 56-66.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  24. Liposomal temocene (m-THPPo) photodynamic treatment induces cell death by mitochondria-independent apoptosis. / Soriano, Jorge; Garcia-Diaz, Maria; Mora, Margarita; Sagristá, Maria Lluïsa; Nonell, Santi; Villanueva, Angeles; Stockert, Juan Carlos; Cañete, Magdalena.

    I: BBA General Subjects, Bind 1830, Nr. 10, 28.05.2013, s. 4611-4620.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  25. Udgivet

    Pattern-oriented Agent-based Monte Carlo simulation of Cellular Redox Environment. / Tang, Jiaowei; Holcombe, Mike ; Boonen, Harrie C.M.

    2013. Poster session præsenteret ved DRA Summer School 2013, Copenhagen, Danmark.

    Publikation: KonferencebidragPosterForskning

  26. Udgivet

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat. / Thing, Mette; Lu, Yi; Agårdh, Li; Larsen, Claus Selch; Ostergaard, Jesper; He, Wei; Wu, Wei; Larsen, Frank; Larsen, Susan Weng.

    I: International Journal of Pharmaceutics, Bind 451, Nr. 1-2, 15.07.2013, s. 34-40.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  27. Udgivet

    Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT). / Aksu, Buket; De Beer, Thomas; Folestad, Staffan; Ketolainen, Jarkko; Lindén, Hans; Lopes, Joao Almeida; de Matas, Marcel; Oostra, Wim; Rantanen, Jukka; Weimer, Marco.

    I: European Journal of Pharmaceutical Sciences, Bind 47, Nr. 2, 29.09.2012, s. 402-405.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  28. Udgivet

    Håb om at ramme latente bakterier i deres skjul. / Bahnsen, Jesper Søborg; Water, Jorrit Jeroen; Foged, Camilla; Franzyk, Henrik; Nielsen, Hanne Mørck.

    I: Lægemiddelforskning 2012, Bind 2012, 2012, s. 12-14.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  29. Udgivet

    Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane exctraction. / Balchen, Marte; Lund, Hanne ; Reubsaet, Léon; Pedersen-Bjergaard, Stig.

    I: Analytica Chimica Acta, Bind 716, 2012, s. 16-23.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  30. Udgivet

    In vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against Taenia Solium cysts. / Cederberg, S.; Sikasunge, C.S.; Andersson, Åsa; Johansen, Maria Vang.

    I: Journal of Parasitology Research, Bind 2012, 2012.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  31. Udgivet

    Role of excipients on solid-state properties of piroxicam during processing. / Christensen, Niels Peter Aae; Cornett, Claus; Rantanen, Jukka.

    I: Journal of Pharmaceutical Sciences, Bind 101, Nr. 3, 2012, s. 1202-1211.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  32. Udgivet

    Drugs for the neglected disease malaria based on natural products. / Christensen, Søren Brøgger; Bygbjerg, Ib Christian.

    Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. red. / Corrado Tringali. 2. udg. Boca Raton : CRC Press, 2012. s. 525-550.

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskning

  33. Udgivet

    Concise synthesis of new bridged-nicotine analogues. / Crestey, François; Hooyberghs, Geert ; Kristensen, Jesper Langgaard.

    I: Tetrahedron, Bind 68, Nr. 5, 04.02.2012, s. 1417-1421.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  34. Udgivet

    In vitro digestion testing of lipid-based delivery systems : calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. / Devraj, Ravi; Williams, Hywel D; Warren, Dallas B; Mullertz, Anette; Porter, Christopher J H; Pouton, Colin W.

    I: International Journal of Pharmaceutics, Bind 441, Nr. 1-2, 2012, s. 323-333.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  35. Udgivet

    Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies. / Escudier, B; Osanto, S; Ljungberg, B; Porta, C; Wagstaff, John; Mulders, Peter; Gore, Martin; Bex, A; Bellmunt, Jaquim; Bracarda, Sergio; Franklin, Alex; Honoré, Per Gustaf Hartvig; Ravaud, Alain; Stein, Jeanne van; Aziz, Zeb ; Akaza, Hideyuki .

    I: Cancer Treatment Reviews, Bind 38, Nr. 2, 2012, s. 127-132.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  36. Udgivet

    License to kill : formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. / Foged, Camilla; Hansen, Jon; Agger, Else Marie.

    I: European Journal of Pharmaceutical Sciences, Bind 45, Nr. 4, 2012, s. 482-491.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  37. Udgivet

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection. / Gammelgaard, Bente; Rasmussen, Laura Hyrup; Gabel-Jensen, Charlotte; Steffansen, Bente.

    I: Biological Trace Element Research, Bind 145, Nr. 2, 2012, s. 248-256.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  38. Udgivet

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS. / Gammelgaard, Bente; Stürup, Stefan; Christensen, Malene Vinther.

    I: Metallomics, Bind 4, Nr. 2, 2012, s. 149-155.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  39. Udgivet

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca. / González, Carlos Rodriguez-Navas; Björklund, Erland; Forteza, Rafael; Cerdà, Victor.

    I: International Journal of Environmental Analytical Chemistry, Bind 92, Nr. 12, 2012, s. 1-16, iFirst.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  40. Udgivet

    Introduction to pharmaceutical chemical analysis. / Hansen, Steen Honore'; Pedersen-Bjergaard, Stig; Rasmussen, Knut Einar.

    Chichester : Wiley, 2012. 477 s.

    Publikation: Bog/antologi/afhandling/rapportBogUndervisningfagfællebedømt

  41. Udgivet

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. / Haq, S Raza; Chi, Celestine N; Bach, Anders; Dogan, Jakob; Engström, Åke; Hultqvist, Greta; Karlsson, O. Andreas; Lundström, Patrik; Montemiglio, Linda Celeste; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    I: Journal of the American Chemical Society, Bind 134, Nr. 1, 01.2012, s. 599-605.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  42. Udgivet

    An electrochemical approach to protein adsorption at charged interfaces. / Hartvig, Rune Andersen.

    København : Det Farmaceutiske Fakultet, 2012. 127 s.

    Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

  43. Udgivet

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.

    I: Langmuir, Bind 28, Nr. 3, 2012, s. 1804-1815.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  44. Udgivet

    Forced degradation of therapeutic proteins. / Hawe, Andrea; Wiggenhorn, Michael; van de Weert, Marco; Garbe, Joerg H. O.; Mahler, Hanns-Christian; Jiskoot, Wim.

    I: Journal of Pharmaceutical Sciences, Bind 101, Nr. 3, 2012, s. 895-913.

    Publikation: Bidrag til tidsskriftReview

  45. Udgivet

    Evaluation of the antibacterial activity of Chilean plants traditionally used for wound healing therapy against multidrug-resistant Staphylococcus aureus. / Holler, Jes Gitz; Søndergaard, Karen ; Slotved, Hans-Christian; Gúzman, Alfonso; Mølgaard, Per.

    I: Planta Medica, Bind 78, Nr. 2, 01.2012, s. 200-205.

    Publikation: Bidrag til tidsskriftLetter

  46. Udgivet

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful. / Holm, Rene; Hesselkilde, Janne Z.; Jørgensen, Erling B.; Müllertz, Anette.

    I: European Journal of Pharmaceutical Sciences, Bind 47, 2012, s. 347-351.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  47. Udgivet

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    I: Journal of Controlled Release, Bind 157, Nr. 1, 2012, s. 141-148.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  48. Udgivet

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    I: Pharmaceutical Research, Bind 29, 2012, s. 669-682.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  49. Udgivet

    Interaction of peptidomimetics with bilayer membranes : biophysical characterization and cellular uptake. / Jing, Xiaona; Kasimova, Marina Robertovna; Simonsen, Anders H.; Jørgensen, Lene; Malmsten, Martin; Franzyk, Henrik; Foged, Camilla.

    I: Langmuir, Bind 28, Nr. 11, 2012, s. 5167-5175.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

  50. Udgivet

    Quality assessment of Tulbaghia rhizomes. / Jäger, Anna; Stafford, Gary Ivan.

    I: South African Journal of Botany, Bind 82, 09.2012, s. 92-98.

    Publikation: Bidrag til tidsskriftTidsskriftartikel

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