A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

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A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. / Sarkodie, F; Ullum, H; Owusu-Dabo, E; Owusu-Ofori, S; Owusu-Ofori, A; Hassall, O.

I: Transfusion Medicine, Bind 26, Nr. 1, 02.2016, s. 63-6.

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

Harvard

Sarkodie, F, Ullum, H, Owusu-Dabo, E, Owusu-Ofori, S, Owusu-Ofori, A & Hassall, O 2016, 'A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana' Transfusion Medicine, bind 26, nr. 1, s. 63-6. https://doi.org/10.1111/tme.12279

APA

Sarkodie, F., Ullum, H., Owusu-Dabo, E., Owusu-Ofori, S., Owusu-Ofori, A., & Hassall, O. (2016). A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. Transfusion Medicine, 26(1), 63-6. https://doi.org/10.1111/tme.12279

Vancouver

Sarkodie F, Ullum H, Owusu-Dabo E, Owusu-Ofori S, Owusu-Ofori A, Hassall O. A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. Transfusion Medicine. 2016 feb;26(1):63-6. https://doi.org/10.1111/tme.12279

Author

Sarkodie, F ; Ullum, H ; Owusu-Dabo, E ; Owusu-Ofori, S ; Owusu-Ofori, A ; Hassall, O. / A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. I: Transfusion Medicine. 2016 ; Bind 26, Nr. 1. s. 63-6.

Bibtex

@article{8c21953d21b14ef8ba1187a8496c9a56,
title = "A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana",
abstract = "OBJECTIVE: To implement and describe a novel syphilis screening strategy for blood donors.BACKGROUND: The seroprevalence of syphilis in blood donors is often high in low- and middle-income countries (LMIC) although the proportion of infectious donations is probably low. Syphilis screening may not happen at all; or the use of non-specific screening tests, which have high false positive rates, results in many donations being discarded unnecessarily. This can have a critical effect on already inadequate blood supplies.MATERIALS AND METHODS: Blood donors were screened at the time of donation with an anti-treponemal rapid diagnostic test (RDT) and blood collected irrespective of the result. Units screening negative for syphilis, human immunodeficiency virus (HIV) and hepatitis B and C were released to stock. RDT screen-positive units were re-tested with rapid plasma reagin (RPR) - units testing negative were released to stock and test-positive units discarded.RESULTS: Of the 2213 blood donors, 182 (8·2{\%}; 182/2213) screened positive by RDT. In addition, 38 out of these 182 (20·9{\%}) were RPR positive on post-donation testing. Over 2 months there was a 79{\%} reduction in blood units discarded due to a positive syphilis screen.CONCLUSION: In other LMIC, this novel strategy can contribute to improving blood safety without jeopardising blood supply.",
keywords = "Adult, Blood Donors, Donor Selection, Female, Ghana, Hospitals, Teaching, Humans, Male, Syphilis, Journal Article",
author = "F Sarkodie and H Ullum and E Owusu-Dabo and S Owusu-Ofori and A Owusu-Ofori and O Hassall",
note = "{\circledC} 2016 British Blood Transfusion Society.",
year = "2016",
month = "2",
doi = "10.1111/tme.12279",
language = "English",
volume = "26",
pages = "63--6",
journal = "Transfusion Medicine",
issn = "0958-7578",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana

AU - Sarkodie, F

AU - Ullum, H

AU - Owusu-Dabo, E

AU - Owusu-Ofori, S

AU - Owusu-Ofori, A

AU - Hassall, O

N1 - © 2016 British Blood Transfusion Society.

PY - 2016/2

Y1 - 2016/2

N2 - OBJECTIVE: To implement and describe a novel syphilis screening strategy for blood donors.BACKGROUND: The seroprevalence of syphilis in blood donors is often high in low- and middle-income countries (LMIC) although the proportion of infectious donations is probably low. Syphilis screening may not happen at all; or the use of non-specific screening tests, which have high false positive rates, results in many donations being discarded unnecessarily. This can have a critical effect on already inadequate blood supplies.MATERIALS AND METHODS: Blood donors were screened at the time of donation with an anti-treponemal rapid diagnostic test (RDT) and blood collected irrespective of the result. Units screening negative for syphilis, human immunodeficiency virus (HIV) and hepatitis B and C were released to stock. RDT screen-positive units were re-tested with rapid plasma reagin (RPR) - units testing negative were released to stock and test-positive units discarded.RESULTS: Of the 2213 blood donors, 182 (8·2%; 182/2213) screened positive by RDT. In addition, 38 out of these 182 (20·9%) were RPR positive on post-donation testing. Over 2 months there was a 79% reduction in blood units discarded due to a positive syphilis screen.CONCLUSION: In other LMIC, this novel strategy can contribute to improving blood safety without jeopardising blood supply.

AB - OBJECTIVE: To implement and describe a novel syphilis screening strategy for blood donors.BACKGROUND: The seroprevalence of syphilis in blood donors is often high in low- and middle-income countries (LMIC) although the proportion of infectious donations is probably low. Syphilis screening may not happen at all; or the use of non-specific screening tests, which have high false positive rates, results in many donations being discarded unnecessarily. This can have a critical effect on already inadequate blood supplies.MATERIALS AND METHODS: Blood donors were screened at the time of donation with an anti-treponemal rapid diagnostic test (RDT) and blood collected irrespective of the result. Units screening negative for syphilis, human immunodeficiency virus (HIV) and hepatitis B and C were released to stock. RDT screen-positive units were re-tested with rapid plasma reagin (RPR) - units testing negative were released to stock and test-positive units discarded.RESULTS: Of the 2213 blood donors, 182 (8·2%; 182/2213) screened positive by RDT. In addition, 38 out of these 182 (20·9%) were RPR positive on post-donation testing. Over 2 months there was a 79% reduction in blood units discarded due to a positive syphilis screen.CONCLUSION: In other LMIC, this novel strategy can contribute to improving blood safety without jeopardising blood supply.

KW - Adult

KW - Blood Donors

KW - Donor Selection

KW - Female

KW - Ghana

KW - Hospitals, Teaching

KW - Humans

KW - Male

KW - Syphilis

KW - Journal Article

U2 - 10.1111/tme.12279

DO - 10.1111/tme.12279

M3 - Letter

VL - 26

SP - 63

EP - 66

JO - Transfusion Medicine

JF - Transfusion Medicine

SN - 0958-7578

IS - 1

ER -

ID: 180570156