Find en forsker – Københavns Universitet

Jesper Langgaard Kristensen

Jesper Langgaard Kristensen

Lektor

Primære forskningsområder

Research interests

Generally medicinal chemistry and the development of new methodology for the construction of compound classes of relevance to medicinal chemistry. Using these tools we are trying to develop new probes and tools that will help us to elucidate the underlying mechanisms responsible for the regulation of different pharmacological targets: Ion channels, enzymes and GPCR’s.

Please see group web-page for more informantion.

 - Member of the Horizon2020 “Click-It” consortium receiving 6 mio. Euro (2015-2020) where we are developing a new imaging technology based on in-vivo click-chemistry.

 - Member of the Marie Curie ETN "AlphaSy" consortium receiving 4.1 mio. Euro (2018-2022) where we are developing a new imaging agents to diagnose Parkisons disease at an early stage.

 - Coordinator of the ETN-EID project SAFER receiving 1.3 mio. Euro (2017-2021). SAFER aims to identify functionally Selective Agonists for the 5-HT2A Serotonin Receptor.

Udvalgte publikationer

  1. Udgivet

    Metabolic fate of hallucinogenic NBOMes

    Leth-Petersen, S., Gabel-Jensen, C., Gillings, N., Lehel, S., Hansen, H. D., Knudsen, G. M. & Kristensen, J. L., 2016, I : Chemical Research in Toxicology. 29, 1, s. 96–100 5 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  2. Udgivet

    Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT7 Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs

    Herth, M. M., Andersen, V. L., Hansen, H. D., Stroth, N., Volk, B., Lehel, S., Dyssegaard, A., Ettrup, A., Svenningsson, P., Knudsen, G. M. & Kristensen, J. L., 13 apr. 2015, I : Journal of Medicinal Chemistry. 58, 8, s. 3631–3636 16 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  3. Udgivet

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, A. A., Lehel, S., Gillings, N., Herth, M. M., Knudsen, G. M. & Kristensen, J. L., 2016, I : Bioorganic & Medicinal Chemistry. 24, s. 5353-5356 4 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  4. Udgivet

    Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors

    Petersen, I. N., Crestey, F., Jensen, A. A., Indurthi, D. C., Pedersen, H., Andreasen, J. T., Balle, T. & Kristensen, J. L., 9 apr. 2015, I : A C S Medicinal Chemistry Letters. 6, 4, s. 472-475 4 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  5. Udgivet

    Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists

    Hansen, M., Phonekeo, K., Paine, J. S., Leth-Petersen, S., Begtrup, M., Bräuner-Osborne, H. & Kristensen, J. L., 7 jan. 2014, I : A C S Chemical Neuroscience. 5, 3, s. 243-249 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  6. Udgivet

    Design, synthesis and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists

    Crestey, F., Jensen, A. A., Borch, M., Andreasen T., J., Andersen, J., Balle, T. & Kristensen, J. L., 2013, I : Journal of Medicinal Chemistry. 56, 23, s. 9673-9682

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

ID: 1305029