Duc Ninh Nguyen
Lektor
Current research focus
I am leading the research group "Cellular and Molecular Pediatrics", at the section for Comparative Pediatrics and Nutrition, Department of Veterinary and Animal Sciences (IVH), SUND, KU. Our research focuses on
1. Impact of perinatal complications (preterm birth, pre-/post-natal infection and inflammation) on immune development in early life.
2. Host, nutritional status and microbe interaction to determine health in early life.
3. Immunometabolic mechanisms in neonatal infectious diseases (neonatal sepsis, necrotizing enterocolitis-NEC) and novel therapeutic approaches.
Our research platforms and tools are based on: 1) preterm pig model of neonatal sepsis and NEC; 2) observational studies in human preterm infant cohorts; 3) multi-omic analyses (transcriptomics, proteomics, gut microbiome); 4) External collaborations with Danish and international hospitals/research centers working with newborn infants, neonatal mice and preterm lambs.
For prospective MSc and PhD students, and postdocs
We are continuously looking for MSc students who are interested in biomedical/immunological research using animal models of neonatal diseases and immune cell in vitro models. Further, we constantly seek external grants for potential PhD students and Postdocs with similar research interests.
Mulige interessekonflikter
The research has received grants from public/independent funding bodies (Novo Nordisk Foundation, Innovation Fond Denmark, Independent Research Fund Denmark), industry (Takeda, Biofiber-Damino, Arla Foods Ingredients, Arla Foods Amba, Danone), and joint research center between industry and public institutions (center of Arla Food for Health).
Udvalgte publikationer
- Udgivet
Glucose supply and glycolysis inhibition shape the clinical fate of Staphylococcus epidermidis-infected preterm newborns
Muk (Mudi), Tik, Brunse, Anders, Henriksen, Nicole Lind, Aasmul-Olsen, Karoline & Nguyen, Duc Ninh, 2022, I: JCI Insight. 7, 11, 18 s., e157234.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Udgivet
Enteral broad-spectrum antibiotics antagonize the effect of fecal microbiota transplantation in preterm pigs
Brunse, Anders, Offersen, Simone Margaard, Mosegaard, J. J., Deng, Ling, Damborg, Peter Panduro, Nielsen, Dennis Sandris, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2021, I: Gut Microbes. 13, 1, s. 1-16 16 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Udgivet
Prenatal inflammation suppresses blood Th1 polarization and gene clusters related to cellular energy metabolism in preterm newborns
Ren, S., Pan, Xiaoyu, Gao, Fei, Sangild, Per Torp & Nguyen, Duc Ninh, 2020, I: FASEB Journal. 34, 2, s. 2896-2911 16 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Udgivet
Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs
Nguyen, Duc Ninh, Thymann, Thomas, Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., Damborg, Peter Panduro, Brunse, Anders, van Gorp, C., Kramer, B. W., Wolfs, T. G. & Sangild, Per Torp, 2018, I: American Journal of Pathology. 188, 11, s. 2629-2643 15 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
ID: 34453716
Flest downloads
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1270
downloads
Protective effects of transforming growth factor β2 in intestinal epithelial cells by regulation of proteins associated with stress and endotoxin responses
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet -
199
downloads
Delayed development of systemic immunity in preterm pigs as a model for preterm infants
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet -
163
downloads
Bovine Milk Oligosaccharides with Sialyllactose for Preterm Piglets
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet