Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity

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Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity. / Trinh, Thi Dieu Binh; Quach, Tam T. T.; Bui, Dung N.; Stærk, Dan; Nguyen, Lien-Hoa D.; Jäger, Anna K.

I: Fitoterapia, Bind 118, 2017, s. 126-131.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Trinh, TDB, Quach, TTT, Bui, DN, Stærk, D, Nguyen, L-HD & Jäger, AK 2017, 'Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity', Fitoterapia, bind 118, s. 126-131. https://doi.org/10.1016/j.fitote.2017.03.003

APA

Trinh, T. D. B., Quach, T. T. T., Bui, D. N., Stærk, D., Nguyen, L-H. D., & Jäger, A. K. (2017). Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity. Fitoterapia, 118, 126-131. https://doi.org/10.1016/j.fitote.2017.03.003

Vancouver

Trinh TDB, Quach TTT, Bui DN, Stærk D, Nguyen L-HD, Jäger AK. Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity. Fitoterapia. 2017;118:126-131. https://doi.org/10.1016/j.fitote.2017.03.003

Author

Trinh, Thi Dieu Binh ; Quach, Tam T. T. ; Bui, Dung N. ; Stærk, Dan ; Nguyen, Lien-Hoa D. ; Jäger, Anna K. / Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity. I: Fitoterapia. 2017 ; Bind 118. s. 126-131.

Bibtex

@article{7758d0497bdd4dc4a53373b4ee68b207,
title = "Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity",
abstract = "Three new xanthones, oblongixanthone F-H (1-3), along with eight known xanthones (4-11), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated by spectroscopic analysis including 1D- and 2D-NMR spectroscopy and mass spectrometry. The antidiabetic effects of all isolated compounds were evaluated by in vitro α-glucosidase and PTP1B inhibition assays. Compound 11 was the most active compound, and inhibited α-glucosidase and PTP1B with IC50 values of 1.7 ± 0.5 and 14.1 ± 3.5 μM, respectively",
author = "Trinh, {Thi Dieu Binh} and Quach, {Tam T. T.} and Bui, {Dung N.} and Dan St{\ae}rk and Nguyen, {Lien-Hoa D.} and J{\"a}ger, {Anna K}",
year = "2017",
doi = "10.1016/j.fitote.2017.03.003",
language = "English",
volume = "118",
pages = "126--131",
journal = "Fitoterapia",
issn = "1971-551X",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity

AU - Trinh, Thi Dieu Binh

AU - Quach, Tam T. T.

AU - Bui, Dung N.

AU - Stærk, Dan

AU - Nguyen, Lien-Hoa D.

AU - Jäger, Anna K

PY - 2017

Y1 - 2017

N2 - Three new xanthones, oblongixanthone F-H (1-3), along with eight known xanthones (4-11), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated by spectroscopic analysis including 1D- and 2D-NMR spectroscopy and mass spectrometry. The antidiabetic effects of all isolated compounds were evaluated by in vitro α-glucosidase and PTP1B inhibition assays. Compound 11 was the most active compound, and inhibited α-glucosidase and PTP1B with IC50 values of 1.7 ± 0.5 and 14.1 ± 3.5 μM, respectively

AB - Three new xanthones, oblongixanthone F-H (1-3), along with eight known xanthones (4-11), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated by spectroscopic analysis including 1D- and 2D-NMR spectroscopy and mass spectrometry. The antidiabetic effects of all isolated compounds were evaluated by in vitro α-glucosidase and PTP1B inhibition assays. Compound 11 was the most active compound, and inhibited α-glucosidase and PTP1B with IC50 values of 1.7 ± 0.5 and 14.1 ± 3.5 μM, respectively

U2 - 10.1016/j.fitote.2017.03.003

DO - 10.1016/j.fitote.2017.03.003

M3 - Journal article

C2 - 28322990

VL - 118

SP - 126

EP - 131

JO - Fitoterapia

JF - Fitoterapia

SN - 1971-551X

ER -

ID: 174043664