Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Dokumenter

  • Fulltext

    Forlagets udgivne version, 1,37 MB, PDF-dokument

Aim
To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI).

Materials and Methods
From the Danish nationwide registries, patients with first-time MI between 2000 and 2015 were divided into three groups according to oral health care within 1 year prior to first-time MI. A multiple logistic regression model provided adjusted odds ratios (ORs) with 95% confidence intervals (CIs) to assess the 3-year risk of major adverse cardiovascular events (MACE).

Results
A total of 103,949 patients were included. Patients with treated periodontitis (PD) prior to first-time MI had an adjusted 3-year risk of MACE similar to patients presumed periodontally healthy (OR 0.97 [95% CI 0.92–1.03]). Patients with no prior dental visits were significantly older, had more comorbidities and showed significantly increased adjusted 3-year risks of MACE (OR 1.47 [95% CI 1.42–1.52]), cardiovascular death (OR 1.71 [95% CI 1.64–1.78]) and heart failure (OR 1.13 [95% CI 1.07–1.20]) compared with patients presumed periodontally healthy.

Conclusions
Patients with treated PD 1 year prior to first-time MI had a similar risk of recurrent cardiovascular events as patients presumed periodontally healthy. No dental visit prior to first-time MI was an independent risk factor for recurrent events.
OriginalsprogEngelsk
TidsskriftJournal of Clinical Periodontology
Vol/bind50
Udgave nummer10
Sider (fra-til)1305-1314
Antal sider10
ISSN0303-6979
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
This work was funded by the Greater Copenhagen Health Science Partners (Clinical Academic Group: Greater Copenhagen Research Centre for Low‐Grade Systemic Inflammation [PRH, PH, CD, CHN]), the Novo Nordisk Foundation (NNF170C0025100 [PRH]), the Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte (CardioHGH) and Helsefonden (20‐B‐0276 [AKW]).

Publisher Copyright:
© 2023 The Authors. Journal of Clinical Periodontology published by John Wiley & Sons Ltd.

Antal downloads er baseret på statistik fra Google Scholar og www.ku.dk


Ingen data tilgængelig

ID: 361318643