The HETE Is on FFAR1 and Pancreatic Islet Cells

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

It is known but generally unappreciated that the fatty acid receptor FFAR1 (GPR40) is responsible for a major part of glucose-induced insulin secretion. This puzzling fact is now explained by Tunaru et al. (2018), who demonstrate that glucose-induced 20-hydroxyeicosatetraenoic acid (20-HETE) amplifies insulin secretion through autocrine activation of FFAR1.

OriginalsprogEngelsk
TidsskriftCell Metabolism
Vol/bind27
Udgave nummer2
Sider (fra-til)273-275
Antal sider3
ISSN1550-4131
DOI
StatusUdgivet - 2018

ID: 189764824