Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

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Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort
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Margit Hørup Larsen
Albrechtsen, Anders
Lise Wegner Thørner
Thomas Werge
Thomas Hansen
Gether, Ulrik
Eva Haastrup
Henrik Ullum

Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine production.

Originalsprog	Engelsk
Artikelnummer	e66262
Tidsskrift	PLOS ONE
Vol/bind	8
Udgave nummer	6
Antal sider	6
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0066262
Status	Udgivet - 2013

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