Fmoc-Based Assembly of PNA Oligomers: Manual and Microwave-Assisted Automated Synthesis
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Fmoc-Based Assembly of PNA Oligomers : Manual and Microwave-Assisted Automated Synthesis. / Shaikh, Ashif Yasin; Hansen, Anna Mette; Franzyk, Henrik.
Peptide Nucleic Acids: Methods and Protocols. red. / Peter E. Nielsen. Humana Press, 2020. s. 1-16 (Methods in molecular biology (Clifton, N.J.), Bind 2105).Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Fmoc-Based Assembly of PNA Oligomers
T2 - Manual and Microwave-Assisted Automated Synthesis
AU - Shaikh, Ashif Yasin
AU - Hansen, Anna Mette
AU - Franzyk, Henrik
PY - 2020
Y1 - 2020
N2 - Exploration of PNA-peptide conjugates as potential antisense antibiotics necessitates a fast and efficient synthesis protocols for amounts that facilitate determination of structure-activity relationships and in vivo studies in animal infection models. Fmoc/Boc-protected PNA monomers are here used for assembly of oligomers by optimized protocols involving either a manual synthesis method at room temperature or automated microwave-assisted coupling of monomers on a peptide synthesizer.
AB - Exploration of PNA-peptide conjugates as potential antisense antibiotics necessitates a fast and efficient synthesis protocols for amounts that facilitate determination of structure-activity relationships and in vivo studies in animal infection models. Fmoc/Boc-protected PNA monomers are here used for assembly of oligomers by optimized protocols involving either a manual synthesis method at room temperature or automated microwave-assisted coupling of monomers on a peptide synthesizer.
U2 - 10.1007/978-1-0716-0243-0_1
DO - 10.1007/978-1-0716-0243-0_1
M3 - Book chapter
C2 - 32088861
SN - 978-1-0716-0242-3
T3 - Methods in molecular biology (Clifton, N.J.)
SP - 1
EP - 16
BT - Peptide Nucleic Acids
A2 - null, Peter E. Nielsen
PB - Humana Press
ER -
ID: 269723379