Fmoc-Based Assembly of PNA Oligomers: Manual and Microwave-Assisted Automated Synthesis
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
Exploration of PNA-peptide conjugates as potential antisense antibiotics necessitates a fast and efficient synthesis protocols for amounts that facilitate determination of structure-activity relationships and in vivo studies in animal infection models. Fmoc/Boc-protected PNA monomers are here used for assembly of oligomers by optimized protocols involving either a manual synthesis method at room temperature or automated microwave-assisted coupling of monomers on a peptide synthesizer.
Originalsprog | Engelsk |
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Titel | Peptide Nucleic Acids : Methods and Protocols |
Redaktører | Peter E. Nielsen |
Antal sider | 16 |
Forlag | Humana Press |
Publikationsdato | 2020 |
Sider | 1-16 |
ISBN (Trykt) | 978-1-0716-0242-3 |
ISBN (Elektronisk) | 978-1-0716-0243-0 |
DOI | |
Status | Udgivet - 2020 |
Navn | Methods in molecular biology (Clifton, N.J.) |
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Vol/bind | 2105 |
ISSN | 1064-3745 |
ID: 269723379