Extraction across supported liquid membranes by use of electrical fields
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The method of electrokinetic migration that used electrical fields to extract supported liquid membranes (SLM) was demonstrated. Several hydrophobic basic drug substances were extracted protonated molecules from a 300 μL acidic sample solution through a SLM, consisting 15 μL 2-nitropheynl octyl ether (NPOE) into 30 μL 10 mmol L-1hydrochloric acid (HCL) as the acceptor solution, applying 300 V dc. The electrical potential difference was the force driving extraction of the charged analytes, without any pH gradient across the SLM. The use of electrical potential difference was found to be a significant driving force for SLM extraction a pH gradient. The kinetic advantage of using electrical field was found also found to be significant, when extractions were performed from small sample volumes.
Originalsprog | Engelsk |
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Tidsskrift | Analytical and Bioanalytical Chemistry |
Vol/bind | 388 |
Udgave nummer | 3 |
Sider (fra-til) | 521-523 |
Antal sider | 3 |
ISSN | 1618-2642 |
DOI | |
Status | Udgivet - 1 jun. 2007 |
ID: 231651215