Estimating drop-out probabilities of STR alleles accounting for stutters, detection threshold truncation and degradation
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Allelic drop-out continues to be a challenge to forensic geneticists when interpreting crime scene evidence and calculating the evidential weight. Methods exist for estimating the probability of allelic drop-out, where the most promising methods use the signal intensities as input for quantifying the drop-out probability. Using data from real crime cases, we demonstrate that taking degradation of the biological material and truncation of the data due to a detection threshold into account is superior to previous approaches. An additional correction for stuttering effects showed limited improvement.
Originalsprog | Engelsk |
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Tidsskrift | Forensic Science International: Genetics Supplement Series |
Vol/bind | 4 |
Udgave nummer | 1 |
Sider (fra-til) | e51-e52 |
ISSN | 1875-1768 |
DOI | |
Status | Udgivet - 2013 |
Bibliografisk note
Funding Information:
This work was in part funded by Aalborg University and University of Copenhagen .
ID: 301362879