Estimating drop-out probabilities of STR alleles accounting for stutters, detection threshold truncation and degradation

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Allelic drop-out continues to be a challenge to forensic geneticists when interpreting crime scene evidence and calculating the evidential weight. Methods exist for estimating the probability of allelic drop-out, where the most promising methods use the signal intensities as input for quantifying the drop-out probability. Using data from real crime cases, we demonstrate that taking degradation of the biological material and truncation of the data due to a detection threshold into account is superior to previous approaches. An additional correction for stuttering effects showed limited improvement.

OriginalsprogEngelsk
TidsskriftForensic Science International: Genetics Supplement Series
Vol/bind4
Udgave nummer1
Sider (fra-til)e51-e52
ISSN1875-1768
DOI
StatusUdgivet - 2013

Bibliografisk note

Funding Information:
This work was in part funded by Aalborg University and University of Copenhagen .

ID: 301362879