Chelating chloride using binuclear lanthanide complexes in water

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Standard

Chelating chloride using binuclear lanthanide complexes in water. / Alexander, Carlson; Thom, James A.; Kenwright, Alan M.; Christensen, Kirsten E.; Sørensen, Thomas Just; Faulkner, Stephen.

I: Chemical Science, Bind 14, Nr. 5, 2023, s. 1194-1204.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Alexander, C, Thom, JA, Kenwright, AM, Christensen, KE, Sørensen, TJ & Faulkner, S 2023, 'Chelating chloride using binuclear lanthanide complexes in water', Chemical Science, bind 14, nr. 5, s. 1194-1204. https://doi.org/10.1039/d2sc05417e

APA

Alexander, C., Thom, J. A., Kenwright, A. M., Christensen, K. E., Sørensen, T. J., & Faulkner, S. (2023). Chelating chloride using binuclear lanthanide complexes in water. Chemical Science, 14(5), 1194-1204. https://doi.org/10.1039/d2sc05417e

Vancouver

Alexander C, Thom JA, Kenwright AM, Christensen KE, Sørensen TJ, Faulkner S. Chelating chloride using binuclear lanthanide complexes in water. Chemical Science. 2023;14(5):1194-1204. https://doi.org/10.1039/d2sc05417e

Author

Alexander, Carlson ; Thom, James A. ; Kenwright, Alan M. ; Christensen, Kirsten E. ; Sørensen, Thomas Just ; Faulkner, Stephen. / Chelating chloride using binuclear lanthanide complexes in water. I: Chemical Science. 2023 ; Bind 14, Nr. 5. s. 1194-1204.

Bibtex

@article{6d088744d22142c2bb4838b5cea38b8a,

title = "Chelating chloride using binuclear lanthanide complexes in water",

abstract = "Halide recognition by supramolecular receptors and coordination complexes in water is a long-standing challenge. In this work, we report chloride binding in water and in competing media by pre-organised binuclear kinetically inert lanthanide complexes, bridged by flexible -(CH2)2- and -(CH2)3- spacers, forming [Ln2(DO3A)2C-2] and [Ln2(DO3A)2C-3], respectively. These hydrophilic, neutral lanthanide coordination complexes are shown to bind chloride with apparent association constants of up to 105 M−1 in water and in buffered systems. Hydroxide bridging was observed in these complexes at basic pH, which was proven to be overcome by chloride. Thus, these lanthanide complexes show promise towards chloride recognition in biology and beyond. The results described here have clearly identified a new area of anion coordination chemistry that is ripe for detailed exploration.",

author = "Carlson Alexander and Thom, {James A.} and Kenwright, {Alan M.} and Christensen, {Kirsten E.} and S{\o}rensen, {Thomas Just} and Stephen Faulkner",

note = "Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry.",

year = "2023",

doi = "10.1039/d2sc05417e",

language = "English",

volume = "14",

pages = "1194--1204",

journal = "Chemical Science",

issn = "2041-6520",

publisher = "Royal Society of Chemistry",

number = "5",

}

RIS

TY - JOUR

T1 - Chelating chloride using binuclear lanthanide complexes in water

AU - Alexander, Carlson

AU - Thom, James A.

AU - Kenwright, Alan M.

AU - Christensen, Kirsten E.

AU - Sørensen, Thomas Just

AU - Faulkner, Stephen

PY - 2023

Y1 - 2023

N2 - Halide recognition by supramolecular receptors and coordination complexes in water is a long-standing challenge. In this work, we report chloride binding in water and in competing media by pre-organised binuclear kinetically inert lanthanide complexes, bridged by flexible -(CH2)2- and -(CH2)3- spacers, forming [Ln2(DO3A)2C-2] and [Ln2(DO3A)2C-3], respectively. These hydrophilic, neutral lanthanide coordination complexes are shown to bind chloride with apparent association constants of up to 105 M−1 in water and in buffered systems. Hydroxide bridging was observed in these complexes at basic pH, which was proven to be overcome by chloride. Thus, these lanthanide complexes show promise towards chloride recognition in biology and beyond. The results described here have clearly identified a new area of anion coordination chemistry that is ripe for detailed exploration.

AB - Halide recognition by supramolecular receptors and coordination complexes in water is a long-standing challenge. In this work, we report chloride binding in water and in competing media by pre-organised binuclear kinetically inert lanthanide complexes, bridged by flexible -(CH2)2- and -(CH2)3- spacers, forming [Ln2(DO3A)2C-2] and [Ln2(DO3A)2C-3], respectively. These hydrophilic, neutral lanthanide coordination complexes are shown to bind chloride with apparent association constants of up to 105 M−1 in water and in buffered systems. Hydroxide bridging was observed in these complexes at basic pH, which was proven to be overcome by chloride. Thus, these lanthanide complexes show promise towards chloride recognition in biology and beyond. The results described here have clearly identified a new area of anion coordination chemistry that is ripe for detailed exploration.

U2 - 10.1039/d2sc05417e

DO - 10.1039/d2sc05417e

M3 - Journal article

C2 - 36756316

AN - SCOPUS:85146183741

VL - 14

SP - 1194

EP - 1204

JO - Chemical Science

JF - Chemical Science

SN - 2041-6520

IS - 5

ER -

ID: 334465007