Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022: Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022

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In 2021 and 2022, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses were detected in one harbor seal and in one adult and three fox cubs in Denmark. The viruses were closely related to contemporary viruses found in Europe, and some had obtained amino acid substitutions related to mammalian adaptation. Notably, the virus distribution appeared to have been different in the infected fox cubs, as one exclusively tested positive for the presence of HPAIV in the brain and the other two only in the lung. Collectively, these findings stress the need for increased disease surveillance of wild and farmed mammals.

Bidragets oversatte titelCharacterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022
OriginalsprogEngelsk
Artikelnummere13208
TidsskriftInfluenza and other Respiratory Viruses
Vol/bind17
Udgave nummer10
Antal sider10
ISSN1750-2640
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
We gratefully acknowledge all data contributors, that is, the authors and their originating laboratories responsible for obtaining the specimens, and their submitting laboratories for generating the genetic sequence and metadata and sharing via the GISAID Initiative. We also acknowledge the National Surveillance of Wildlife Diseases in Denmark for coordinating the wild life health surveillance, which is funded by the Danish Ministry of Environment.

Publisher Copyright:
© 2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.

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