Brain expressed microRNAs implicated in schizophrenia etiology

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Thomas Hansen
  • Line Olsen
  • Morten Lindow
  • Klaus D Jakobsen
  • Henrik Ullum
  • Erik Jonsson
  • Ole A Andreassen
  • Srdjan Djurovic
  • Ingrid Melle
  • Ingrid Agartz
  • Håkan Hall
  • Sally Timm
  • Wang, August Gabriel
  • Werge, Thomas
Protein encoding genes have long been the major targets for research in schizophrenia genetics. However, with the identification of regulatory microRNAs (miRNAs) as important in brain development and function, miRNAs genes have emerged as candidates for schizophrenia-associated genetic factors. Indeed, the growing understanding of the regulatory properties and pleiotropic effects that miRNA have on molecular and cellular mechanisms, suggests that alterations in the interactions between miRNAs and their mRNA targets may contribute to phenotypic variation.
TidsskriftP L o S One
Udgave nummer9
Sider (fra-til)e873
StatusUdgivet - 2007

ID: 48591659