An evaluation of twelve nested models of transperitoneal transport of urea: the one-compartment assumption is valid

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Standard

An evaluation of twelve nested models of transperitoneal transport of urea : the one-compartment assumption is valid. / Graff, J; Fugleberg, S; Joffe, P; Brahm, J; Fogh-Andersen, N.

I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 55, Nr. 4, 07.1995, s. 331-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Graff, J, Fugleberg, S, Joffe, P, Brahm, J & Fogh-Andersen, N 1995, 'An evaluation of twelve nested models of transperitoneal transport of urea: the one-compartment assumption is valid', Scandinavian Journal of Clinical & Laboratory Investigation, bind 55, nr. 4, s. 331-9.

APA

Graff, J., Fugleberg, S., Joffe, P., Brahm, J., & Fogh-Andersen, N. (1995). An evaluation of twelve nested models of transperitoneal transport of urea: the one-compartment assumption is valid. Scandinavian Journal of Clinical & Laboratory Investigation, 55(4), 331-9.

Vancouver

Graff J, Fugleberg S, Joffe P, Brahm J, Fogh-Andersen N. An evaluation of twelve nested models of transperitoneal transport of urea: the one-compartment assumption is valid. Scandinavian Journal of Clinical & Laboratory Investigation. 1995 jul.;55(4):331-9.

Author

Graff, J ; Fugleberg, S ; Joffe, P ; Brahm, J ; Fogh-Andersen, N. / An evaluation of twelve nested models of transperitoneal transport of urea : the one-compartment assumption is valid. I: Scandinavian Journal of Clinical & Laboratory Investigation. 1995 ; Bind 55, Nr. 4. s. 331-9.

Bibtex

@article{efa016419d95428db3115aa71ebb4810,
title = "An evaluation of twelve nested models of transperitoneal transport of urea: the one-compartment assumption is valid",
abstract = "Models of transperitoneal urea transport are generally based on the one-compartment assumption, i.e. that the plasma water urea concentration in the peritoneal capillary bed is equal to the plasma water urea concentration in the peripheral veins. The aim of this study was to investigate the mechanism(s) of transperitoneal urea transport and to test the one-compartment assumption for urea. A total of 12 nested models were formulated and validated on the basis of experimental results obtained from 23 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that transperitoneal transport of urea probably involves diffusion, non-lymphatic convection and lymphatic convection. It was furthermore demonstrated that the inclusion of lymphatic convection changes the mass transfer area coefficient considerably. Finally, no deviation from the one-compartment assumption was demonstrated by our results.",
keywords = "Adult, Aged, Biological Transport, Diffusion, Female, Humans, Male, Middle Aged, Models, Biological, Peritoneal Dialysis, Peritoneum, Urea, Water",
author = "J Graff and S Fugleberg and P Joffe and J Brahm and N Fogh-Andersen",
year = "1995",
month = jul,
language = "English",
volume = "55",
pages = "331--9",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - An evaluation of twelve nested models of transperitoneal transport of urea

T2 - the one-compartment assumption is valid

AU - Graff, J

AU - Fugleberg, S

AU - Joffe, P

AU - Brahm, J

AU - Fogh-Andersen, N

PY - 1995/7

Y1 - 1995/7

N2 - Models of transperitoneal urea transport are generally based on the one-compartment assumption, i.e. that the plasma water urea concentration in the peritoneal capillary bed is equal to the plasma water urea concentration in the peripheral veins. The aim of this study was to investigate the mechanism(s) of transperitoneal urea transport and to test the one-compartment assumption for urea. A total of 12 nested models were formulated and validated on the basis of experimental results obtained from 23 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that transperitoneal transport of urea probably involves diffusion, non-lymphatic convection and lymphatic convection. It was furthermore demonstrated that the inclusion of lymphatic convection changes the mass transfer area coefficient considerably. Finally, no deviation from the one-compartment assumption was demonstrated by our results.

AB - Models of transperitoneal urea transport are generally based on the one-compartment assumption, i.e. that the plasma water urea concentration in the peritoneal capillary bed is equal to the plasma water urea concentration in the peripheral veins. The aim of this study was to investigate the mechanism(s) of transperitoneal urea transport and to test the one-compartment assumption for urea. A total of 12 nested models were formulated and validated on the basis of experimental results obtained from 23 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that transperitoneal transport of urea probably involves diffusion, non-lymphatic convection and lymphatic convection. It was furthermore demonstrated that the inclusion of lymphatic convection changes the mass transfer area coefficient considerably. Finally, no deviation from the one-compartment assumption was demonstrated by our results.

KW - Adult

KW - Aged

KW - Biological Transport

KW - Diffusion

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Models, Biological

KW - Peritoneal Dialysis

KW - Peritoneum

KW - Urea

KW - Water

M3 - Journal article

C2 - 7569736

VL - 55

SP - 331

EP - 339

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 4

ER -

ID: 94518906