Jette Sandholm Jensen Kastrup

Professor

Strukturbiologi
Universitetsparken 2
2100 København Ø
- jsk@sund.ku.dk
- https://ilf.ku.dk/
Telefon: +4535336486

ORCID: 0000-0003-2654-1510

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2024
Udgivet
Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators
Francotte, P., Bay, Yasmin, Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., de Tullio, P., Beaufour, C., Botez, I., Pickering, Darryl S, Frydenvang, Karla Andrea, Danober, L., Kristensen, A. S., Kastrup, Jette Sandholm Jensen & Pirotte, B., 2024, I: European Journal of Medicinal Chemistry. 264, 15 s., 116036.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet
Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface
Nørgrd Larsen, Andreas, Perozzo, A. M., Biggin, P. C., Bowie, D. & Kastrup, Jette Sandholm Jensen, 2024, I: Journal of Biological Chemistry. 300, 3, 10 s., 105717.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure
Bay, Yasmin, Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, Anders Skov, Boesen, T., Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2024, I: FEBS Journal. 291, 7, s. 1506-1529
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet
The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2
Bay, Yasmin, Egeberg Jeppesen, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Pickering, Darryl S, Kristensen, Anders Skov & Kastrup, Jette Sandholm Jensen, 2024, I: FEBS Letters. 598, 7, s. 743-757
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

ID: 1298590

Forskning

Jette Sandholm Jensen Kastrup

Strukturbiologi

Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators

Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2

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Structure of rat acidic fibroblast growth factor at 1.4 A resolution.