Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes

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Standard

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. / Hamid, Y H; Rose, C S; Urhammer, S A; Glümer, C; Nolsøe, R; Kristiansen, O P; Mandrup-Poulsen, Thomas; Borch-Johnsen, K; Jorgensen, T; Hansen, T; Pedersen, O.

In: Diabetologia, Vol. 48, No. 2, 01.02.2005, p. 251-60.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hamid, YH, Rose, CS, Urhammer, SA, Glümer, C, Nolsøe, R, Kristiansen, OP, Mandrup-Poulsen, T, Borch-Johnsen, K, Jorgensen, T, Hansen, T & Pedersen, O 2005, 'Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes', Diabetologia, vol. 48, no. 2, pp. 251-60. https://doi.org/10.1007/s00125-004-1623-0

APA

Hamid, Y. H., Rose, C. S., Urhammer, S. A., Glümer, C., Nolsøe, R., Kristiansen, O. P., Mandrup-Poulsen, T., Borch-Johnsen, K., Jorgensen, T., Hansen, T., & Pedersen, O. (2005). Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. Diabetologia, 48(2), 251-60. https://doi.org/10.1007/s00125-004-1623-0

Vancouver

Hamid YH, Rose CS, Urhammer SA, Glümer C, Nolsøe R, Kristiansen OP et al. Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. Diabetologia. 2005 Feb 1;48(2):251-60. https://doi.org/10.1007/s00125-004-1623-0

Author

Hamid, Y H ; Rose, C S ; Urhammer, S A ; Glümer, C ; Nolsøe, R ; Kristiansen, O P ; Mandrup-Poulsen, Thomas ; Borch-Johnsen, K ; Jorgensen, T ; Hansen, T ; Pedersen, O. / Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. In: Diabetologia. 2005 ; Vol. 48, No. 2. pp. 251-60.

Bibtex

@article{1cd6fbd4d5334fe184dab4cf56c67b2b,
title = "Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes",
abstract = "The cytokine interleukin 6 (IL-6) is an essential regulator of the acute phase response associated with insulin-resistant states including type 2 diabetes and obesity. Three polymorphisms at positions -597, -572, and -174 of the IL6 promoter have been reported to influence IL6 transcription. The aim of this study was to investigate whether the IL6 promoter polymorphisms were associated with features of the WHO-defined metabolic syndrome and related quantitative traits in 7,553 Caucasian Danes.",
keywords = "Base Sequence, Cohort Studies, DNA Primers, Denmark, European Continental Ancestry Group, Female, Gene Frequency, Genetic Variation, Genotype, Humans, Interleukin-6, Male, Metabolic Syndrome X, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Promoter Regions, Genetic",
author = "Hamid, {Y H} and Rose, {C S} and Urhammer, {S A} and C Gl{\"u}mer and R Nols{\o}e and Kristiansen, {O P} and Thomas Mandrup-Poulsen and K Borch-Johnsen and T Jorgensen and T Hansen and O Pedersen",
year = "2005",
month = feb,
day = "1",
doi = "10.1007/s00125-004-1623-0",
language = "English",
volume = "48",
pages = "251--60",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes

AU - Hamid, Y H

AU - Rose, C S

AU - Urhammer, S A

AU - Glümer, C

AU - Nolsøe, R

AU - Kristiansen, O P

AU - Mandrup-Poulsen, Thomas

AU - Borch-Johnsen, K

AU - Jorgensen, T

AU - Hansen, T

AU - Pedersen, O

PY - 2005/2/1

Y1 - 2005/2/1

N2 - The cytokine interleukin 6 (IL-6) is an essential regulator of the acute phase response associated with insulin-resistant states including type 2 diabetes and obesity. Three polymorphisms at positions -597, -572, and -174 of the IL6 promoter have been reported to influence IL6 transcription. The aim of this study was to investigate whether the IL6 promoter polymorphisms were associated with features of the WHO-defined metabolic syndrome and related quantitative traits in 7,553 Caucasian Danes.

AB - The cytokine interleukin 6 (IL-6) is an essential regulator of the acute phase response associated with insulin-resistant states including type 2 diabetes and obesity. Three polymorphisms at positions -597, -572, and -174 of the IL6 promoter have been reported to influence IL6 transcription. The aim of this study was to investigate whether the IL6 promoter polymorphisms were associated with features of the WHO-defined metabolic syndrome and related quantitative traits in 7,553 Caucasian Danes.

KW - Base Sequence

KW - Cohort Studies

KW - DNA Primers

KW - Denmark

KW - European Continental Ancestry Group

KW - Female

KW - Gene Frequency

KW - Genetic Variation

KW - Genotype

KW - Humans

KW - Interleukin-6

KW - Male

KW - Metabolic Syndrome X

KW - Polymerase Chain Reaction

KW - Polymorphism, Single Nucleotide

KW - Promoter Regions, Genetic

U2 - 10.1007/s00125-004-1623-0

DO - 10.1007/s00125-004-1623-0

M3 - Journal article

C2 - 15645209

VL - 48

SP - 251

EP - 260

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 2

ER -

ID: 33902487