Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years
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Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years. / Bliddal, Mette; Pottegård, Anton; Kirkegaard, Hans; Olsen, J; Sørensen, T I A; Nohr, E A.
In: Obesity Science & Practice, Vol. 2, No. 4, 12.2016, p. 415-425.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years
AU - Bliddal, Mette
AU - Pottegård, Anton
AU - Kirkegaard, Hans
AU - Olsen, J
AU - Sørensen, T I A
AU - Nohr, E A
PY - 2016/12
Y1 - 2016/12
N2 - OBJECTIVE: This study aimed to examine how weight and weight changes related to pregnancy were associated with depressive symptoms 11-16 years after childbirth.METHOD: We followed 16,998 first-time mothers from the Danish National Birth Cohort up till 16 years after birth and estimated associations between depressive symptoms and pre-pregnancy body mass index (BMI) (kg m(-2)), weight changes in different time periods, and BMI-adjusted waist circumference 7 years after birth (WCBMI, cm). Depressive symptoms were estimated by the Center for Epidemiologic Studies Depression 10-item scale. Multiple logistic regression analyses were used to estimate odds ratios (OR) and 95% confidence intervals.RESULTS: Compared with normal-weight, we found that underweight, overweight and obesity were associated with greater odds of depressive symptoms (1.29, 1.24 and 1.73, respectively). Compared with weight change ±1 BMI unit during the total follow-up period, greater odds for depressive symptoms were observed with weight loss (OR 1.14, 0.96-1.36) or gain of 2-2.99 kg m(-2) (OR 1.11, 0.92-1.33) or gain of ≥3 kg m(-2) (OR 1.68, 1.46-1.94). WCBMI > 2.2 cm was associated with greater odds of depressive symptoms (OR 1.16, 0.99-1.36) than waist circumference as predicted by BMI.CONCLUSION: Low and high pre-pregnancy BMI, weight changes and WCBMI larger than predicted were associated with more depressive symptoms in midlife.
AB - OBJECTIVE: This study aimed to examine how weight and weight changes related to pregnancy were associated with depressive symptoms 11-16 years after childbirth.METHOD: We followed 16,998 first-time mothers from the Danish National Birth Cohort up till 16 years after birth and estimated associations between depressive symptoms and pre-pregnancy body mass index (BMI) (kg m(-2)), weight changes in different time periods, and BMI-adjusted waist circumference 7 years after birth (WCBMI, cm). Depressive symptoms were estimated by the Center for Epidemiologic Studies Depression 10-item scale. Multiple logistic regression analyses were used to estimate odds ratios (OR) and 95% confidence intervals.RESULTS: Compared with normal-weight, we found that underweight, overweight and obesity were associated with greater odds of depressive symptoms (1.29, 1.24 and 1.73, respectively). Compared with weight change ±1 BMI unit during the total follow-up period, greater odds for depressive symptoms were observed with weight loss (OR 1.14, 0.96-1.36) or gain of 2-2.99 kg m(-2) (OR 1.11, 0.92-1.33) or gain of ≥3 kg m(-2) (OR 1.68, 1.46-1.94). WCBMI > 2.2 cm was associated with greater odds of depressive symptoms (OR 1.16, 0.99-1.36) than waist circumference as predicted by BMI.CONCLUSION: Low and high pre-pregnancy BMI, weight changes and WCBMI larger than predicted were associated with more depressive symptoms in midlife.
U2 - 10.1002/osp4.75
DO - 10.1002/osp4.75
M3 - Journal article
C2 - 28090347
VL - 2
SP - 415
EP - 425
JO - Obesity Science & Practice
JF - Obesity Science & Practice
SN - 2055-2238
IS - 4
ER -
ID: 180935183