Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

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There is substantial evidence that mitochondrial dysfunction is linked to insulin resistance and is present in several tissues relevant to the pathogenesis of type 2 diabetes. Here, we examined whether common variation in genes involved in oxidative phosphorylation (OxPhos) contributes to type 2 diabetes susceptibility or influences diabetes-related metabolic traits.
Original languageEnglish
Issue number2
Pages (from-to)340-8
Number of pages9
Publication statusPublished - 2012

ID: 40208768