Mogens Holst Nissen

Mogens Holst Nissen

Professor

Member of:


    1. 2024
    2. Published

      Chemokine Receptor Profile of T Cells and Progression Rate of Geographic Atrophy Secondary to Age-related Macular Degeneration

      Martinez Villarruel Hinnerskov, J., Krogh Nielsen, M., Thomsen, Alexander Kai, Steffensen, Maria Abildgaard, Honoré, B., Vorum, H., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2 Jan 2024, In: Investigative Ophthalmology & Visual Science (Online). 65, 1, p. 5

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Neuroretinal degeneration in a mouse model of systemic chronic immune activation observed by proteomics

      Khan, A. M., Steffensen, Maria Abildgaard, Paskeviciute, E., Abduljabar, A. B., Sørensen, Torben Lykke, Vorum, H., Nissen, Mogens Holst & Honoré, B., 2024, In: Frontiers in Immunology. 15, 15 p., 1374617.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2023
    5. Published

      Complement factor H Y402H polymorphism results in diminishing CD4+T cells and increasing C-reactive protein in plasma.

      Nielsen, M. K., Subhi, Y., Falk, Mads Krüger, Singh, Amardeep, Sørensen, Torben Lykke, Nissen, Mogens Holst & Faber, Carsten, 8 Nov 2023, In: Scientific Reports. 13, 1, 9 p., 19414.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Systemic virus infection results in CD8 T cell recruitment to the retina in the absence of local virus infection

      Paskeviciute, E., Chen, M., Xu, H., Honoré, B., Vorum, H., Sørensen, Torben Lykke, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Nissen, Mogens Holst & Steffensen, Maria Abildgaard, 2023, In: Frontiers in Immunology. 14, 1221511.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2022
    8. Published

      Complement activation by RPE cells preexposed to TNFα and IFNγ

      Udsen, M., Tagmose, C., Garred, Peter, Nissen, Mogens Holst & Faber, Carsten, 2022, In: Experimental Eye Research. 218, 108982.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2020
    10. Published

      Chemokine Profile and the Alterations in CCR5-CCL5 Axis in Geographic Atrophy Secondary to Age-Related Macular Degeneration

      Krogh Nielsen, M., Subhi, Y., Molbech, C. R., Falk, Mads Krüger, Nissen, Mogens Holst & Sørensen, Torben Lykke, 2020, In: Investigative Ophthalmology & Visual Science. 61, 4, 7 p., 28.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 2019
    12. Published

      Association of CD11b+ Monocytes and Anti-Vascular Endothelial Growth Factor Injections in Treatment of Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

      Subhi, Y., Krogh Nielsen, M., Molbech, C. R., Falk, M. K., Singh, A., Hviid, Thomas Vauvert F., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: J A M A Ophthalmology. 137, 5, p. 515-522 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ

      Faber, Carsten, Juel, H. B., Jensen, Benjamin Anderschou Holbech, Christensen, Jan Pravsgaard, Prause, J. U., Thomsen, Allan Randrup & Nissen, Mogens Holst, 2019, In: Investigative Ophthalmology & Visual Science. 60, 1, p. 192-201 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Imbalances in tissue inhibitors of metalloproteinases differentiate choroidal neovascularization from geographic atrophy

      Krogh Nielsen, M., Subhi, Y., Molbech, C. R., Nilsson, L. L., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: Acta Ophthalmologica. 97, 1, p. 84-90

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Patients with a fast progression profile in geographic atrophy have increased CD200 expression on circulating monocytes.

      Nielsen, M. K., Subhi, Y., Molbech, C., Falk, M., Singh, A., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: Clinical and Experimental Ophthalmology. 47, 1, p. 69-78

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Plasma markers of chronic low-grade inflammation in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration

      Subhi, Y., Krogh Nielsen, M., Molbech, C. R., Oishi, A., Singh, A., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: Acta Ophthalmologica. 97, 1, p. 99-106

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Polypoidal Choroidal Vasculopathy Associate With Diminished Regulatory T Cells That Are Polarized Into a T Helper 2-Like Phenotype

      Subhi, Y., Krogh Nielsen, M., Molbech, C. R., Oishi, A., Singh, A., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: Investigative Ophthalmology & Visual Science. 60, 5, p. 2583-2590

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Systemic levels of interleukin-6 correlate with progression rate of geographic atrophy secondary to age-related macular degeneration.

      Krogh Nielsen, M., Subhi, Y., Molbech, C. R., Falk, M. K., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2019, In: Investigative Ophthalmology & Visual Science. 60, p. 202-208

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2018
    20. Published

      Extended HLA-G haplotypes in patients with age-related macular degeneration

      Svendsen, S. G., Nilsson, L. L., Djurisic, S., Funck, T., Wu, C., Faber, Carsten, Falk, M. K., Singh, A., Sørensen, Torben Lykke, Carosella, E. D., LeMaoult, J., Hviid, Thomas Vauvert F. & Nissen, Mogens Holst, 2018, In: HLA. 92, 2, p. 83-89 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2017
    22. Published

      Expression and differential regulation of HLA-G isoforms in the retinal pigment epithelial cell line, ARPE-19

      Svendsen, S. G., Udsen, M. S., Daouya, M., Funck, T., Wu, C., Carosella, E. D., LeMaoult, J., Hviid, Thomas Vauvert F., Faber, Carsten & Nissen, Mogens Holst, 1 May 2017, In: Human Immunology. 78, 5-6, p. 414-420 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      CD11b and CD200 on Circulating Monocytes Differentiate Two Angiographic Subtypes of Polypoidal Choroidal Vasculopathy

      Subhi, Y., Nielsen, M. K., Molbech, C., Oishi, A., Singh, A., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2017, In: Investigative Ophthalmology & Visual Science. 58, 12, p. 5242-5250

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      T-cell differentiation and CD56+ levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration

      Subhi, Y., Nielsen, M. K., Molbech, C., Oishi, A., Singh, A., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2017, In: Aging. 9, 11, p. 2436-2452

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2016
    26. Published

      Induction of Chemokine Secretion and Monocyte Migration by Human Choroidal Melanocytes in Response to Proinflammatory Cytokines

      Jehs, T., Faber, Carsten, Udsen, M. S., Jager, M. J., Clark, S. J. & Nissen, Mogens Holst, Dec 2016, In: Investigative Ophthalmology & Visual Science. 57, 15, p. 6568-6579 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      HLA-G gene polymorphisms in patients with age-related macular degeneration

      Svendsen, S. G., Nilsson, L. L., Djurisic, S., Funck, T., Faber, Carsten, Falk, M. K., Singh, A., Sørensen, Torben Lykke, Hviid, Thomas Vauvert F. & Nissen, Mogens Holst, Sep 2016, In: Investigative Ophthalmology & Visual Science. 57, 12, 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    28. 2015
    29. Published

      Druser og AMD

      Nissen, Mogens Holst, Sep 2015, In: Oftalmolog. p. 19-22 4 p.

      Research output: Contribution to journalJournal articleCommunication

    30. Published

      EXPRESSION OF HLA-G IN THE RETINAL PIGMENT EPITHELIAL CELLS AND ITS IMPORTANCE FOR THE DEVELOPMENT OF AGE-RELATED MACULAR DEGENERATION

      Svendsen, S. G., Daouya, M., Wu, C., Faber, Carsten, Falk, M. K., Singh, A., Sørensen, Torben Lykke, Hviid, Thomas Vauvert F., Carosella, E. D., LeMaoult, J. & Nissen, Mogens Holst, Aug 2015, In: HLA. 86, 2, p. 76-77 2 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    31. Published

      Systemic and Ocular Long Pentraxin 3 in Patients with Age-Related Macular Degeneration

      Juel, H. B., Faber, Carsten, Fog, L. M., Bastrup-Birk, S., Reese-Petersen, A. L., Falk, M. K., Singh, A., Sørensen, Torben Lykke, Garred, Peter & Nissen, Mogens Holst, 15 Jul 2015, In: P L o S One. 10, 7, p. 1-12 e0132800.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Early and exudative age-related macular degeneration is associated with increased plasma levels of soluble TNF receptor II

      Faber, Carsten, Jehs, T., Juel, H. B., Singh, A., Falk, M. K., Sørensen, Torben Lykke & Nissen, Mogens Holst, May 2015, In: Acta Ophthalmologica. 93, 3, p. 242-47 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. 2014
    34. Published

      Inflammation-induced chemokine expression in uveal melanoma cell lines stimulates monocyte chemotaxis

      Jehs, T., Faber, Carsten, Juel, H. B., Bronkhorst, I. H. G., Jager, M. J. & Nissen, Mogens Holst, Aug 2014, In: Investigative Ophthalmology & Visual Science. 55, 8, p. 5169-75 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration

      Falk, M. K., Singh, A., Faber, Carsten, Nissen, Mogens Holst, Hviid, Thomas Vauvert F. & Sørensen, Torben Lykke, 8 May 2014, In: Investigative Ophthalmology & Visual Science. 55, 7, p. 4050-4056 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Blood expression levels of chemokine receptor CCR3 and chemokine CCL11 in age-related macular degeneration: a case-control study

      Falk, M. K., Singh, A., Faber, Carsten, Nissen, Mogens Holst, Hviid, Thomas Vauvert F. & Sørensen, Torben Lykke, 27 Feb 2014, In: B M C Ophthalmology. 14, 1, p. 1-7 8 p., 22.

      Research output: Contribution to journalJournal articleResearch

    37. Published

      CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine/Chemokine Receptor Complex in Patients with AMD

      Falk, M. K., Singh, A., Faber, Carsten, Nissen, Mogens Holst, Hviid, Thomas Vauvert F. & Sørensen, Torben Lykke, 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e112473.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Calcium-independent phospholipase A2, group VIA, is critical for RPE cell survival

      Kolko, Miriam, Vohra, Rupali, van der Burght, B. W., Poulsen, K. & Nissen, Mogens Holst, 2014, In: Molecular Vision. 20, p. 511–521

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. 2013
    40. Published

      Age-related macular degeneration is associated with increased proportion of CD56(+) T cells in peripheral blood

      Faber, Carsten, Singh, A., Krüger Falk, M., Juel, H. B., Sørensen, Torben Lykke & Nissen, Mogens Holst, Nov 2013, In: Ophthalmology. 120, 11, p. 2310-6 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells

      van der Burght, B. W., Hansen, M., Olsen, Jørgen, Zhou, J., Wu, Y., Nissen, Mogens Holst & Sparrow, J. R., Nov 2013, In: Acta Ophthalmologica (Online). 91, 7, p. e537-e545

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      The expression and functional activity of membrane-bound human leukocyte antigen-G1 are influenced by the 3'-untranslated region

      Svendsen, S. G., Hantash, B. M., Zhao, L., Faber, Carsten, Bzorek, M., Nissen, Mogens Holst & Hviid, Thomas Vauvert F., Jul 2013, In: Human Immunology. 74, 7, p. 818-27 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Autophagy and survival of retinal pigment epithelial cells

      Juel, H. B., Faber, Carsten, Svendsen, S. G., Vallejo, A. N. & Nissen, Mogens Holst, 2013. 1 p.

      Research output: Contribution to conferencePosterResearch

    44. Published

      Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death

      Juel, H. B., Faber, Carsten, Svendsen, S. G., Vallejo, A. N. & Nissen, Mogens Holst, 2013, In: PLOS ONE. 8, 5, p. 1-10 10 p., e64619.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. 2012
    46. Published

      Chemokine Expression in Retinal Pigment Epithelial ARPE-19 Cells in Response to Coculture with Activated T Cells

      Juel, H. B., Faber, Carsten, Udsen, M. S., Folkersen, L. & Nissen, Mogens Holst, Dec 2012, In: Investigative Ophthalmology & Visual Science. 53, 13, p. 8472-8480 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Complement factor H deficiency results in decreased neuroretinal expression of Cd59a in aged mice

      Faber, Carsten, Williams, J., Juel, H. B., Greenwood, J., Nissen, Mogens Holst & Moss, S. E., 19 Sep 2012, In: Investigative Ophthalmology & Visual Science. 53, 10, p. 6324-6330 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Altered expression of CD46 and CD59 on leukocytes in neovascular age-related macular degeneration.

      Singh, A., Faber, Carsten, Falk, M., Nissen, Mogens Holst, Hviid, Thomas Vauvert F. & Sørensen, Torben Lykke, 2012, In: American Journal of Ophthalmology. 154, 1, p. 193-199

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. 2011
    50. Published

      Astrocytoma cells upregulate expression of pro-inflammatory cytokines after co-culture with activated peripheral blood mononuclear cells

      Jehs, T. M. L., Faber, Carsten, Juel, H. B. & Nissen, Mogens Holst, 2011, In: APMIS: Acta Pathologica, Microbiologica et Immunologica Scandinavica. 119, 8, p. 551-561

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Retinal pigment epithelial cells upregulate expression of complement factors after co-culture with activated T cells

      Juel, H. B., Kaestel, C., Folkersen, L., Faber, Carsten, Heegaard, N. H. H., Borup, R. & Nissen, Mogens Holst, 2011, In: Experimental Eye Research. 92, 3, p. 180-88

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. 2010
    53. Published

      Glycosaminoglycans enhance the fibrillation propensity of the ß2-microglobulin cleavage variant--¿K58-ß2m

      Corlin, D. B., Johnsen, C. K., Nissen, Mogens Holst & Heegaard, N. H. H., 12 Nov 2010, In: Biochemical and Biophysical Research Communications. 402, 2, p. 247-51 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells

      Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Retinal immune privilege: indoleamine dioxygenase (IDO)

      Juel, H. B., Faber, Carsten, Jehs, T. M. L., Kæstel, C. & Nissen, Mogens Holst, 2010.

      Research output: Contribution to conferencePosterResearch

    56. 2009
    57. Published

      A beta2-microglobulin cleavage variant fibrillates at near-physiological pH

      Corlin, D. B., Johnsen, C. K., Nissen, Mogens Holst & Heegaard, N. H. H., 2009, In: Biochemical and Biophysical Research Communications. 381, 2, p. 187-91 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Modified human beta 2-microglobulin (desLys(58)) displays decreased affinity for the heavy chain of MHC class I and induces nitric oxide production and apoptosis

      Wang, M., Harhaji, L., Lamberth, K., Harndahl, M., Buus, Søren, Heegaard, N. H. H., Claesson, Mogens Helweg & Nissen, Mogens Holst, 2009, In: Scandinavian Journal of Immunology. 69, 3, p. 203-12 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Orthotopic porcine corneal xenotransplantation using a human graft

      Faber, Carsten, Wang, M., Scherfig, E., Sørensen, K. E., Prause, J. U., Ehlers, N. & Nissen, Mogens Holst, 2009, In: Acta Ophthamologica (Online). 87, 8, p. 917-9 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Retinal pigment epithelial cells upregulate expression of chemokines after co-culture with activated T cells

      Juel, H. B., Kæstel, C., Udsen, M., Faber, Carsten & Nissen, Mogens Holst, 2009.

      Research output: Contribution to conferencePosterResearch

    61. 2008
    62. Published

      Cellular expression or binding of desLys58-beta2 microglobulin is not dependent on the presence of the tri-molecular MHC class I complex.

      Wang, M., Corlin, D. B., Heegaard, N. H. H., Claesson, Mogens Helweg & Nissen, Mogens Holst, 2008, In: Scandinavian Journal of Immunology. 67, 2, p. 105-12 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Immunsystemet og øjet.

      Faber, Carsten & Nissen, Mogens Holst, 2008, In: Ugeskrift for læger. 170, 38, p. 2953-7 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Induction of apoptosis of monocytic leukemic cells by deslys(58) beta 2-microglobulin

      Wang, M., Harhaji, L., Claesson, Mogens Helweg & Nissen, Mogens Holst, 2008, In: Scandinavian Journal of Immunology. 68, 2, p. 214-214

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Upregulation of Complement Factors in ARPE-19 Cells Co-cultured with Activated T Cells

      Juel, H. B., Kæstel, C., Westlund, B. S. & Nissen, Mogens Holst, 2008.

      Research output: Contribution to conferencePosterResearch

    66. Published

      Vitreous humor and albumin augment the proliferation of cultured retinal precursor cells.

      Yang, J., Klassen, H., Pries, M., Wang, W. & Nissen, Mogens Holst, 2008, In: Journal of Neuroscience Research.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. 2007
    68. Published

      Identification of intracellular phospholipases A2 in the human eye: involvement in phagocytosis of photoreceptor outer segments.

      Kolko, Miriam, Wang, J., Zhan, C., Poulsen, K. A., Prause, J. U., Nissen, Mogens Holst, Heegaard, Steffen & Bazan, N. G., 2007, In: Investigative Ophthalmology & Visual Science. 48, 3, p. 1401-9 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published
    70. Published

      Subretinal posterior pole injury induces selective proliferation of RPE cells in the periphery in in vivo studies in pigs

      Kiilgaard, Jens Folke, Prause, J. U., Prause, M., Scherfig, E., Nissen, Mogens Holst & la Cour, Morten, 2007, In: Investigative Ophthalmology & Visual Science. 48, 1, p. 355-60 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. 2006
    72. Published

      An isotonic preparation of 1 mg/ml indocyanine green is not toxic to hyperconfluent ARPE19 cells, even after prolonged exposure

      Kiilgaard, Jens Folke, Nissen, Mogens Holst, la Cour, Morten, Kiilgaard, Jens Folke, Nissen, M. H. & la Cour, Morten, 2006, In: Acta Ophthalmologica Scandinavica. 84, 1, p. 42-6 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Aqueous humor enhances the proliferation of rat retinal precursor cells in culture, and this effect is partially reproduced by ascorbic acid.

      Yang, J., Klassen, H., Pries, M., Wang, W. & Nissen, Mogens Holst, 2006, In: Stem Cells. 24, 12, p. 2766-75 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Identification of MHC class I H-2 Kb/Db-restricted immunogenic peptides derived from retinal proteins.

      Wang, M., Bai, F., Pries, M., Buus, Søren, Prause, J. U. & Nissen, Mogens Holst, 2006, In: Investigative Ophthalmology & Visual Science. 47, 9, p. 3939-45 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Identification of an HLA-A*0201 restricted Bcl2-derived epitope expressed on tumors.

      Wang, M., Johansen, B., Nissen, Mogens Holst, Thorn, M., Kløverpris, H., Fomsgaard, A., Buus, Søren & Claesson, Mogens Helweg, 2006, In: Cancer Letters. 251, 1, p. 86-95 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Interconverting conformations of variants of the human amyloidogenic protein beta2-microglobulin quantitatively characterized by dynamic capillary electrophoresis and computer simulation.

      Heegaard, N. H. H., Jørgensen, T. J. D., Cheng, L., Schou, C., Nissen, Mogens Holst & Trapp, O., 2006, In: Analytical Chemistry. 78, 11, p. 3667-73 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling.

      Met, Özcan, Wang, M., Pedersen, Anders Elm, Nissen, Mogens Holst, Buus, Søren & Claesson, Mogens Helweg, 2006, In: Cancer Letters. 231, 2, p. 247-56 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Variants of beta-microglobulin cleaved at lysine-58 retain the main conformational features of the native protein but are more conformationally heterogeneous and unstable at physiological temperature.

      Mimmi, M. C., Jørgensen, T. J. D., Pettirossi, F., Corazza, A., Viglino, P., Esposito, G., De Lorenzi, E., Giorgetti, S., Pries, M., Corlin, D. B., Nissen, Mogens Holst & Heegaard, N. H. H., 2006, In: FEBS Journal. 273, 11, p. 2461-74 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      [Isolation, culture and identification of rat retinal progenitor cells in vitro]

      Yang, J., Nissen, Mogens Holst & Wang, W., 2006, In: Zhonghua Yanke Zazhi. 42, 2, p. 104-10 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. 2005
    81. Published

      A novel system for continuous protein refolding and on-line capture by expanded bed adsorption.

      Ferré, H., Ruffet, E., Nielsen, L. B., Nissen, Mogens Holst, Hobley, T. J., Thomas, O. R. T. & Buus, Søren, 2005, In: Protein Science. 14, 8, p. 2141-53 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Quantification of cleaved beta2-microglobulin in serum from patients undergoing chronic hemodialysis.

      Corlin, D. B., Sen, J. W., Ladefoged, S., Lund, G. B., Nissen, Mogens Holst & Heegaard, N. H. H., 2005, In: Clinical Chemistry. 51, 7, p. 1177-84 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.

      Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin.

      Heegaard, N. H. H., Jørgensen, T. J. D., Rozlosnik, N., Corlin, D. B., Pedersen, J. S., Tempesta, A. G., Roepstorff, P., Bauer, R. & Nissen, Mogens Holst, 2005, In: Biochemistry. 44, 11, p. 4397-407 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. 2004
    86. Published

      In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

      Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Muligheder for behandling af AMD i fremtiden

      Nissen, Mogens Holst, 2004, In: Værn om Synet. 3, p. 4-9

      Research output: Contribution to journalJournal articleResearch

    88. 2003
    89. Published

      Comparison of CTL reactivity in the spleen and draining lymph nodes after immunization with peptides pulsed on dendritic cells or mixed with Freund's incomplete adjuvant.

      Wang, M., Nissen, Mogens Holst, Buus, Søren, Röpke, C. & Claesson, Mogens Helweg, 2003, In: Immunology Letters. 90, 1, p. 13-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Self-peptides with intermediate capacity to bind and stabilize MHC class I molecules may be immunogenic.

      Andersen, M. L. M., Ruhwald, M., Nissen, Mogens Holst, Buus, Søren & Claesson, Mogens Helweg, 2003, In: Scandinavian Journal of Immunology. 57, 1, p. 21-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      Structural and conformational variants of human beta2-microglobulin characterized by capillary electrophoresis and complementary separation methods.

      Heegaard, N. H. H., Rovatti, L., Nissen, Mogens Holst & Hamdan, M., 2003, In: Journal of Chromatography A. 1004, 1-2, p. 51-9 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. 2002
    93. Published

      Applications of on-line weak affinity interactions in free solution capillary electrophoresis.

      Heegaard, N. H. H., Nissen, Mogens Holst & Chen, D. D. Y., 2002, In: Electrophoresis. 23, 6, p. 815-22 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Cleaved beta 2-microglobulin partially attains a conformation that has amyloidogenic features.

      Heegaard, N. H. H., Roepstorff, P., Melberg, S. G. & Nissen, Mogens Holst, 2002, In: Journal of Biological Chemistry. 277, 13, p. 11184-9 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Establishment of a quantitative ELISA capable of determining peptide - MHC class I interaction.

      Wiborg, Christina Sylvester-Hvid, Kristensen, N., Blicher, T., Ferré, H., Lauemøller, S. L., Wolf, X. A., Lamberth, K., Nissen, Mogens Holst, Pedersen, L. Ø. & Buus, Søren, 2002, In: HLA. 59, 4, p. 251-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.

      Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.

      Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

      Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. 2001
    100. Published

      Conformational intermediate of the amyloidogenic protein beta 2-microglobulin at neutral pH.

      Heegaard, N. H., Sen, J. W., Kaarsholm, N. C. & Nissen, Mogens Holst, 2001, In: Journal of Biological Chemistry. 276, 35, p. 32657-62 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    101. Published

      Efficient assembly of recombinant major histocompatibility complex class I molecules with preformed disulfide bonds.

      Ostergaard Pedersen, L., Nissen, Mogens Holst, Hansen, N. J., Nielsen, L. L., Lauenmøller, S. L., Blicher, T., Nansen, A., Wiborg, Christina Sylvester-Hvid, Thomsen, Allan Randrup & Buus, Søren, 2001, In: European Journal of Immunology. 31, 10, p. 2986-96 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    102. Published

      Identification and design of p53-derived HLA-A2-binding peptides with increased CTL immunogenicity.

      Petersen, T. R., Buus, Søren, Brunak, S., Nissen, Mogens Holst, Sherman, L. A. & Claesson, Mogens Helweg, 2001, In: Scandinavian Journal of Immunology. 53, 4, p. 357-64 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    103. Published

      Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15.

      Thulesen, S., Nissen, Mogens Holst, Ødum, Niels & Röpke, C., 2001, In: Journal of Interferon & Cytokine Research. 21, 11, p. 905-11 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    104. Published

      Lack of FasL expression in cultured human retinal pigment epithelial cells.

      Kaestel, C. G., Madsen, H. O., Prause, J. U., Jørgensen, A., Liang, Y., la Cour , M., Lui, G. M., Odum, N., Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental and Clinical Immunogenetics. 18, 1, p. 34-41 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    105. Published

      Maturation of dendritic cells by recombinant human CD40L-trimer leads to a homogeneous cell population with enhanced surface marker expression and increased cytokine production.

      Würtzen, P. A., Nissen, Mogens Holst & Claesson, Mogens Helweg, 2001, In: Scandinavian Journal of Immunology. 53, 6, p. 579-87 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    106. Published

      Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.

      Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    107. Published

      Quantitative predictions of peptide binding to MHC class I molecules using specificity matrices and anchor-stratified calibrations.

      Lauemøller, S. L., Holm, A., Hilden, Jørgen, Brunak, S., Nissen, Mogens Holst, Buus, Anette Stryhn, Østergaard Pedersen, L., Buus, Søren & Holm, A., 2001, In: HLA. 57, 5, p. 405-14 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    108. Published

      Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.

      Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    109. 2000
    110. Published

      Amino acid substitutions in the melanoma antigen recognized by T cell 1 peptide modulate cytokine responses in melanoma-specific T cells

      Nielsen, M. B., Kirkin, A. F., Loftus, D., Nissen, Mogens Holst, Rivoltini, L., Zeuthen, J., Geisler, Carsten & Odum, N., 2000, In: Journal of Immunotherapy. 23, 4, p. 405-11 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    111. Published

      Bcl-2, Bax, and c-Fos expression correlates to RPE cell apoptosis induced by UV-light and daunorubicin.

      Liang, Y. G., Jorgensen, A. G., Kaestel, C. G., Wiencke, A. K., Lui, G. M., la Cour, Morten, Röpke, C. H. & Nissen, Mogens Holst, 2000, In: Current Eye Research. 20, 1, p. 25-34 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    112. Published

      Congophilicity (Congo red affinity) of different beta2-microglobulin conformations characterized by dye affinity capillary electrophoresis.

      Heegaard, N. H., Sen, J. W. & Nissen, Mogens Holst, 2000, In: Journal of Chromatography A. 894, 1-2, p. 319-27 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    113. Published

      Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

      Thulesen, S., Nielsen, M., Petersen, T. R., Nissen, Mogens Holst, Ødum, N. & Röpke, C., 2000, In: Cytokine. 12, 6, p. 751-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    114. Published

      Splenocytes cultured in low concentrations of IL-2 generate NK cell specificities toward syngenic and allogenic targets.

      Nissen, Mogens Holst, Jeppesen, M. & Claesson, Mogens Helweg, 2000, In: Cellular Immunology. 203, 1, p. 47-54 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    115. 1999
    116. Published

      Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype.

      Claesson, Mogens Helweg, Bregenholt, S., Bonhagen, K., Thoma, S., Möller, P., Grusby, M. J., Leithäuser, F., Nissen, Mogens Holst & Reimann, J., 1999, In: Journal of Immunology. 162, 6, p. 3702-10 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    117. Published

      Human p53(264-272) HLA-A2 binding peptide is an immunodominant epitope in DNA-immunized HLA-A2 transgenic mice.

      Petersen, T. R., Bregenholta, S., Pedersen, L. O., Nissen, Mogens Holst & Claesson, Mogens Helweg, 1999, In: Cancer Letters. 137, 2, p. 183-91 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    118. Published

      In vitro activated CD4+ T cells from interferon-gamma (IFN-gamma)-deficient mice induce intestinal inflammation in immunodeficient hosts.

      Bregenholt, S., Brimnes, J., Nissen, Mogens Holst & Claesson, Mogens Helweg, 1999, In: Clinical and Experimental Immunology. 118, 2, p. 228-34 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    119. Published

      Superantigens are presented by and activate thymocytes from infants.

      Thulesen, S., Jørgensen, A., Gerwien, J., Dohlsten, M., Nissen, Mogens Holst, Ødum, N. & Röpke, C., 1999, In: Experimental and Clinical Immunogenetics. 16, 4, p. 226-33 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    120. 1998
    121. Published

      C1-esterase inhibitor blocks T lymphocyte proliferation and cytotoxic T lymphocyte generation in vitro.

      Nissen, Mogens Holst, Bregenholt, S., Nording, J. A. & Claesson, Mogens Helweg, 1998, In: International Immunology. 10, 2, p. 167-73 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    122. Published

      Human retinal pigment epithelial cell-induced apoptosis in activated T cells.

      Jørgensen, A., Wiencke, A. K., la Cour, Morten, Kaestel, C. G., Madsen, H. O., Hamann, Steffen, Lui, G. M., Scherfig, E., Prause, J. U., Svejgaard, A., Odum, N., Nissen, Mogens Holst & Röpke, C., 1998, In: Investigative Ophthalmology & Visual Science. 39, 9, p. 1590-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    123. 1997
    124. Published

      A simple method for the preparation and purification of C1 complement cleaved beta 2-microglobulin from human serum.

      Nissen, Mogens Holst, Johansen, B. & Bjerrum, Ole Jannik, 1997, In: Journal of Immunological Methods. 205, 1, p. 29-33 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    125. 1996
    126. Published

      MHC class I phenotype and function of human beta 2-microglobulin transgenic murine lymphocytes.

      Bjerager, L., Pedersen, L. O., Bregenholt, S., Nissen, Mogens Holst & Claesson, Mogens Helweg, 1996, In: Scandinavian Journal of Immunology. 44, 6, p. 615-22 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    127. Published

      pH dependence of MHC class I-restricted peptide presentation.

      Buus, Anette Stryhn, Pedersen, L. O., Romme, T., Olsen, A. C., Nissen, Mogens Holst, Thorpe, C. J. & Buus, Søren, 1996, In: Journal of Immunology. 156, 11, p. 4191-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    128. 1995
    129. Published

      Des-Lys58-beta 2m and native beta 2m in rheumatoid arthritis serum and synovial fluid.

      Williams, R. C., Malone, C. C., Nissen, Mogens Holst, Aono, F. M., Vachula, M. & Van Epps, D. E., 1995, In: Clinical and Experimental Rheumatology. 12, 6, p. 635-41 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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