Lasse Kristoffer Bak
Visiting researcher
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
Current research
How do cells employ compartmentalised cAMP and calcium signalling to control function and metabolism? How are these affected in disease and what can we do about that?
Primary fields of research
Brain signalling and metabolism is disturbed in a wide range of neurological and psychiatric diseases.
I aim to understand how compartmentalised cAMP and Ca2+ signalling events dictates brain cell function, and how this is disturbed in disease with the ultimate goal of devising novel pharmacotherapeutic treatments.
To this end, we employ a range of technologies, including cell cultures, tissue models, molecular tools, biosensor-based single cell imaging, and a range of assays to investigate cellular function and metabolism.
Teaching
Teaching:
- Cellular and molecular biology (BSc level, pharmacy program)
- Pharmacology (BSc & MSc levels, pharmacy program)
- Academic project management (PhD course)
Supervision (BSc/MSc thesis projects and PhD projects):
- Cellular biology and pharmacology focusing on how cAMP and calcium signalling dictates cell function
ID: 1303653
Most downloads
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410
downloads
Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
275
downloads
Compartmentalised signalling-metabolism coupling in brain cells - putative drug targets for neurological diseases?
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published -
178
downloads
Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes
Research output: Contribution to conference › Poster › Research
Published