Jens Lykkesfeldt
Professor
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(R)-alfa-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 1999, In: The FASEB Journal. 13, p. 411-4418 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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(R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2-Nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench
Halkier, Barbara Ann, Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 487-491 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats
Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.Research output: Contribution to journal › Journal article › Research › peer-review
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A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537Research output: Contribution to journal › Review › Research › peer-review
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A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2020, In: Paediatric Respiratory Reviews. 33, p. 28-29Research output: Contribution to journal › Comment/debate › Research › peer-review
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Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE−/− mice
Christophersen, D. V., Møller, Peter, Thomsen, Morten Bækgaard, Lykkesfeldt, Jens, Loft, Steffen, Wallin, H., Vogel, U. & Jacobsen, N. R., 2021, In: FASEB Journal. 35, 3, 14 p., e21307.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, Jens, Vinarsky, V., Bartholomew, J. C., Song, M. & Ames, B. N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, p. 9562-9566 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation
Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing
Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.Research output: Contribution to journal › Journal article › Research › peer-review
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An ELISA for detection of complement-bound circulating immune complexes in mice
Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711Research output: Contribution to journal › Review › Research › peer-review
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Animal models in pharmacology and toxicology
Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Antioxidant supplementation does not alter endurance training adaptation
Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.Research output: Contribution to journal › Journal article › Research › peer-review
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Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.Research output: Contribution to journal › Review › Research › peer-review
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Artemisinin induces omeprazole metabolism in human beings
Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Van Huong, N., Niêu, N. T., Sy, N. D., Lykkesfeldt, Jens & Công, L. D., 1 Aug 1998, In: Clinical Pharmacology and Therapeutics. 64, 2, p. 160-167 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used
Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization
Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models
Skerniskyte, J., Mulet, C., André, A. C., Anderson, M. C., Injarabian, L., Buck, A., Prade, V. M., Sansonetti, P. J., Reibel-Foisset, S., Walch, A. K., Lebel, M., Lykkesfeldt, Jens & Marteyn, B. S., 2023, In: Gut Microbes. 15, 2, 18 p., 2271597.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes
Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate maintains a low plasma oxygen level
Injarabian, L., Scherlinger, M., Devin, A., Ransac, S., Lykkesfeldt, Jens & Marteyn, B. S., 2020, In: Scientific Reports. 10, 1, 6 p., 10659.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats
Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3
Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age
Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
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Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study
Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
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Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model
Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.Research output: Contribution to journal › Journal article › Research › peer-review
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BCPT 2023 policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396Research output: Contribution to journal › Journal article › Research › peer-review
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BCPT policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8Research output: Contribution to journal › Review › Research › peer-review
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Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.Research output: Contribution to conference › Paper › Research
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.Research output: Contribution to conference › Paper › Research
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Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-Vitamin mod åreforkalkning
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Aktuel Naturvidenskab. 3, p. 26-29 4 p.Research output: Contribution to journal › Journal article › Communication
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Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
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Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis
Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Charting a new course: A vision for the future as editors-in-chief
Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 390 1 p.Research output: Contribution to journal › Editorial › Research
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Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic dyslipidemia induces fatty liver disease in Guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs
Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin
Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653Research output: Contribution to journal › Journal article › Research › peer-review
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Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone
Böttcher, T., Ren, H., Goiny, M., Gerber, J., Lykkesfeldt, Jens, Kuhnt, U., Lotz, M., Bunkowski, S., Werner, C., Schau, I., Spreer, A., Christen, S. & Nau, R., 2004, In: Journal of Neurochemistry. 91, 6, p. 1450-1460 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels
Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.Research output: Contribution to journal › Journal article › Research › peer-review
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Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes
Fager Ferrari, M., Zetterberg, E., Rossing, Caroline Maria, Manon‐jensen, T., Pehrsson, M., Karsdal, M. A., Lykkesfeldt, Jens & Leinoe, E., 2021, In: Haemophilia. 27, 1, p. e69-e77Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.Research output: Contribution to journal › Journal article › Research › peer-review
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Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults
Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.Research output: Contribution to journal › Journal article › Research › peer-review
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Decreased expression of the GLP-1 receptor after segmental artery injury in mice
Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288Research output: Contribution to journal › Journal article › Research › peer-review
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Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease
Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1995, In: Analytical Biochemistry. 229, p. 329-335Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride
Lykkesfeldt, Jens, 2000, In: Analytical Biochemistry. 282, p. 89-93 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry
Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification
Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs
Weng Larsen, S., Reinvar, E., Svendsen, O., Lykkesfeldt, Jens, Friis, G. J. & Larsen, C., 2001, In: Internation Journal of Pharmaceutics. 230, p. 67-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation
Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis
Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats
Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis
Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives
Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Critical Reviews in Food Science and Nutrition. 61, 5, p. 742-755 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations
Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2002, In: Journal of Veterinary Pharmacology and Therapeutics. 25, 5, p. 335-342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs
Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017-2018
Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 4, 10 p., 892.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies
Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does vitamin C deficiency affect cognitive development and function?
Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency promote fatty liver disease development?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does vitamin C deficiency result in impaired brain development in infants?
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2009, In: Redox Report. 14, 1, p. 2-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does vitamin C matter? A quest for in vivo effects of vitamin C deficiency
Lykkesfeldt, Jens, 2008, In: Free Radical Research. 42, S1, p. s23 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Dyslipidemia: Obese or Not Obese-That Is Not the Question
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412Research output: Contribution to journal › Review › Research › peer-review
- Published
Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model
Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study
Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial
Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 2023, In: Cells. 12, 6, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training
Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies
Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study
Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of smoking cessation on plasma ascorbic acid concentration
Lykkesfeldt, Jens, Priemé, H., Loft, Steffen & Poulsen, Henrik Enghusen, 13 Jul 1996, In: B M J (Clinical Research Edition). 313, 7049, p. 91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of smoking on erythorbic acid pharmacokinetics
Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells
Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia
Lauritzen, B., Lykkesfeldt, Jens, Djurup, R., Flodgaard, H. & Svendsen, O., 2005, In: Pharmacological Research. 51, 6, p. 509-514 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials
Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs
Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4231856
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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