Hüsün Sheyma Kizilkaya

Hüsün Sheyma Kizilkaya

Research Assistant


Publication year:
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  1. 2024
  2. E-pub ahead of print

    Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge

    Gasbjerg, Lærke Smidt, Rasmussen, Rasmus Syberg, Dragan, A., Lindquist, Peter, Melchiorsen, J. U., Stepniewski, T. M., Schiellerup, S., Tordrup, Esther Karen, Gadgaard, S., Kizilkaya, Hüsün Sheyma, Willems, S., Zhong, Y., Wang, Y., Wright, S. C., Lauschke, V. M., Hartmann, Bolette, Holst, Jens Juul, Selent, J. & Rosenkilde, Mette, 2024, (E-pub ahead of print) In: British Journal of Pharmacology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Accepted/In press

    Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

    Kizilkaya, H. S., Sørensen, K. V., Madsen, J. S., Lindquist, P., Douros, J. D., Bork-Jensen, J., Berghella, A., Gerlach, P. A., Gasbjerg, L. S., Mokrosiński, J., Mowery, S. A., Knerr, P. J., Finan, B., Campbell, J. E., D’Alessio, D. A., Perez-Tilve, D., Faas, F., Mathiasen, S., Rungby, J., Sørensen, H. T. & 15 others, Vaag, A., Nielsen, J. S., Holm, Jens-Christian, Lauenborg, J., Damm, Peter, Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Holst, Jens Juul, Hansen, Torben, Wright, S. C., Lauschke, V. M., Grarup, N., Hauser, Alexander Sebastian & Rosenkilde, Mette, 2024, (Accepted/In press) In: Nature Metabolism.

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology

    Rosenkilde, Mette, Lindquist, Peter, Kizilkaya, Hüsün Sheyma & Gasbjerg, Lærke Smidt, 2024, In: Peptides. 177, 14 p., 171212.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2023
  6. Published

    Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

    Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, N., 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice

    Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2021
  10. Published

    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

    Smit, F. X., van der Velden, W. J. C., Kizilkaya, Hüsün Sheyma, Nørskov, A., Lückmann, Michael, Hansen, T. N., wbf943, wbf943, Qvotrup, K., Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: Structure. 29, 7, p. 679-693.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion

    Kuhre, Rune Ehrenreich, Modvig, Ida Marie, Jepsen, Sara Lind, Kizilkaya, Hüsün Sheyma, Bæch-Laursen, C., Smith, C. A., Reimann, F., Gribble, F. M., Rosenkilde, Mette & Holst, Jens Juul, 2021, In: Frontiers in Endocrinology. 12, 12 p., 690387.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

    Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, N. & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Pharmacological and structure-activity relationship studies of oleoyl-lysophosphatidylinositol synthetic mimetics

    Paternoster, S., Simpson, P. V., Kokh, E., Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Mancera, R. L., Keating, D. J., Massi, M. & Falasca, M., 2021, In: Pharmacological Research. 172, 105822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2019
  15. Published

    Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats

    Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 170618194