Wounds in chronic leg oedema

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  • Ewa Anna Burian
  • Karlsmark, Tonny
  • Susan Nørregaard
  • Klaus Kirketerp-Møller
  • Robert Scott Kirsner
  • Peter John Franks
  • Isabelle Quéré
  • Christine Joy Moffatt

Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross-sectional study was to investigate the point-prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63-6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25-3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93-3.60), being male (OR 2.08, 95% CI 1.78-2.44), being over 85 years of age (OR 1.80, 95% CI 1.23-2.62), underweight (OR 1.79, 95% CI 1.14-2.79), bed bound (OR 1.79, 95% CI 1.01-3.16), chair bound (OR 1.52, 95% CI 1.18-1.97), diabetes (OR 1.47, 95% CI 1.23-1.77), and walking with aid (OR 1·41, 95% CI 1.17-1.69). 43.22% of those with wounds had clinically defined well-controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42-0.58, P <.001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19-2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05-2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.

OriginalsprogEngelsk
TidsskriftInternational Wound Journal
Vol/bind19
Udgave nummer2
Sider (fra-til)411-425
Antal sider15
ISSN1742-4801
DOI
StatusUdgivet - 2022

Bibliografisk note

Funding Information:
3M Healthcare provided ILF an unrestricted research grant for the LIMPRINT-project and access and support of an electronic CRF. The authors are grateful to all the patients and staff participating in this study. The study was funded by the International Lymphoedema Framework (ILF) a registered charity, and 3M Healthcare. The medical device company (3M) had no role in the study design, data collection, data analysis, data interpretation, writing, or decision to submit the article for publication. All authors and researchers acted independently from funders.

Funding Information:
3M Healthcare provided ILF an unrestricted research grant for the LIMPRINT‐project and access and support of an electronic CRF. The authors are grateful to all the patients and staff participating in this study. The study was funded by the International Lymphoedema Framework (ILF) a registered charity, and 3M Healthcare. The medical device company (3M) had no role in the study design, data collection, data analysis, data interpretation, writing, or decision to submit the article for publication. All authors and researchers acted independently from funders.

Publisher Copyright:
© 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.

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