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Vitamin d status, filaggrin genotype, and cardiovascular risk factors : a mendelian randomization approach. / Skaaby, Tea; Husemoen, Lise Lotte Nystrup; Martinussen, Torben; Thyssen, Jacob P; Melgaard, Michael; Thuesen, Betina Heinsbæk; Pisinger, Charlotta; Jørgensen, Torben; Johansen, Jeanne D; Menné, Torkil; Carlsen, Berit; Szecsi, Pal B; Stender, Steen; Fenger, Runa Vavia; Fenger, Mogens; Linneberg, Allan.
I:
P L o S One, Bind 8, Nr. 2, 2013, s. e57647.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Skaaby, T, Husemoen, LLN
, Martinussen, T, Thyssen, JP, Melgaard, M, Thuesen, BH, Pisinger, C, Jørgensen, T
, Johansen, JD, Menné, T, Carlsen, B, Szecsi, PB, Stender, S, Fenger, RV, Fenger, M
& Linneberg, A 2013, '
Vitamin d status, filaggrin genotype, and cardiovascular risk factors: a mendelian randomization approach',
P L o S One, bind 8, nr. 2, s. e57647.
https://doi.org/10.1371/journal.pone.0057647APA
Skaaby, T., Husemoen, L. L. N.
, Martinussen, T., Thyssen, J. P., Melgaard, M., Thuesen, B. H., Pisinger, C., Jørgensen, T.
, Johansen, J. D., Menné, T., Carlsen, B., Szecsi, P. B., Stender, S., Fenger, R. V., Fenger, M.
, & Linneberg, A. (2013).
Vitamin d status, filaggrin genotype, and cardiovascular risk factors: a mendelian randomization approach.
P L o S One,
8(2), e57647.
https://doi.org/10.1371/journal.pone.0057647Vancouver
Skaaby T, Husemoen LLN
, Martinussen T, Thyssen JP, Melgaard M, Thuesen BH o.a.
Vitamin d status, filaggrin genotype, and cardiovascular risk factors: a mendelian randomization approach.
P L o S One. 2013;8(2):e57647.
https://doi.org/10.1371/journal.pone.0057647Author
Skaaby, Tea ; Husemoen, Lise Lotte Nystrup ; Martinussen, Torben ; Thyssen, Jacob P ; Melgaard, Michael ; Thuesen, Betina Heinsbæk ; Pisinger, Charlotta ; Jørgensen, Torben ; Johansen, Jeanne D ; Menné, Torkil ; Carlsen, Berit ; Szecsi, Pal B ; Stender, Steen ; Fenger, Runa Vavia ; Fenger, Mogens ; Linneberg, Allan. / Vitamin d status, filaggrin genotype, and cardiovascular risk factors : a mendelian randomization approach. I: P L o S One. 2013 ; Bind 8, Nr. 2. s. e57647.
Bibtex
@article{74ccd098a5904bc1860f68d8a9f07851,
title = "Vitamin d status, filaggrin genotype, and cardiovascular risk factors: a mendelian randomization approach",
abstract = "Vitamin D deficiency is associated with increased cardiovascular disease risk in observational studies. Whether these associations are causal is not clear. Loss-of-function mutations in the filaggrin gene result in up to 10% higher serum vitamin D concentrations, supposedly due to a decreased UV-protection of the keratinocytes. We used a Mendelian randomization approach to estimate the causal effect of vitamin D status on serum lipids, blood pressure, body mass index, waist circumference, and the metabolic syndrome.",
author = "Tea Skaaby and Husemoen, {Lise Lotte Nystrup} and Torben Martinussen and Thyssen, {Jacob P} and Michael Melgaard and Thuesen, {Betina Heinsb{\ae}k} and Charlotta Pisinger and Torben J{\o}rgensen and Johansen, {Jeanne D} and Torkil Menn{\'e} and Berit Carlsen and Szecsi, {Pal B} and Steen Stender and Fenger, {Runa Vavia} and Mogens Fenger and Allan Linneberg",
year = "2013",
doi = "10.1371/journal.pone.0057647",
language = "English",
volume = "8",
pages = "e57647",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",
}
RIS
TY - JOUR
T1 - Vitamin d status, filaggrin genotype, and cardiovascular risk factors
T2 - a mendelian randomization approach
AU - Skaaby, Tea
AU - Husemoen, Lise Lotte Nystrup
AU - Martinussen, Torben
AU - Thyssen, Jacob P
AU - Melgaard, Michael
AU - Thuesen, Betina Heinsbæk
AU - Pisinger, Charlotta
AU - Jørgensen, Torben
AU - Johansen, Jeanne D
AU - Menné, Torkil
AU - Carlsen, Berit
AU - Szecsi, Pal B
AU - Stender, Steen
AU - Fenger, Runa Vavia
AU - Fenger, Mogens
AU - Linneberg, Allan
PY - 2013
Y1 - 2013
N2 - Vitamin D deficiency is associated with increased cardiovascular disease risk in observational studies. Whether these associations are causal is not clear. Loss-of-function mutations in the filaggrin gene result in up to 10% higher serum vitamin D concentrations, supposedly due to a decreased UV-protection of the keratinocytes. We used a Mendelian randomization approach to estimate the causal effect of vitamin D status on serum lipids, blood pressure, body mass index, waist circumference, and the metabolic syndrome.
AB - Vitamin D deficiency is associated with increased cardiovascular disease risk in observational studies. Whether these associations are causal is not clear. Loss-of-function mutations in the filaggrin gene result in up to 10% higher serum vitamin D concentrations, supposedly due to a decreased UV-protection of the keratinocytes. We used a Mendelian randomization approach to estimate the causal effect of vitamin D status on serum lipids, blood pressure, body mass index, waist circumference, and the metabolic syndrome.
U2 - 10.1371/journal.pone.0057647
DO - 10.1371/journal.pone.0057647
M3 - Journal article
C2 - 23460889
VL - 8
SP - e57647
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 2
ER -
