The structure and function of endophilin proteins

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. Here, we discuss the role of endophilins in these processes and summarize novel insights into the molecular aspects of endophilin function. Also, we discuss phosphorylation of endophilins and how this and other mechanisms may contribute to disease.
OriginalsprogEngelsk
TidsskriftCell Biochemistry and Biophysics
Vol/bind60
Udgave nummer3
Sider (fra-til)137-54
Antal sider18
ISSN1085-9195
DOI
StatusUdgivet - 1 jul. 2011

ID: 33793885