The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.
Originalsprog | Engelsk |
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Tidsskrift | HIV Medicine |
Vol/bind | 13 |
Udgave nummer | 1 |
Sider (fra-til) | 62-72 |
Antal sider | 11 |
ISSN | 1464-2662 |
DOI | |
Status | Udgivet - jan. 2012 |
ID: 48505077