The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis. / Hedegaard, Chris J; Krakauer, Martin; Bendtzen, Klaus; Sørensen, Per Soelberg; Sellebjerg, Finn; Nielsen, Claus H.

I: Clinical Immunology, Bind 129, Nr. 1, 01.10.2008, s. 80-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hedegaard, CJ, Krakauer, M, Bendtzen, K, Sørensen, PS, Sellebjerg, F & Nielsen, CH 2008, 'The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis', Clinical Immunology, bind 129, nr. 1, s. 80-9. https://doi.org/10.1016/j.clim.2008.06.007, https://doi.org/10.1016/j.clim.2008.06.007

APA

Hedegaard, C. J., Krakauer, M., Bendtzen, K., Sørensen, P. S., Sellebjerg, F., & Nielsen, C. H. (2008). The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis. Clinical Immunology, 129(1), 80-9. https://doi.org/10.1016/j.clim.2008.06.007, https://doi.org/10.1016/j.clim.2008.06.007

Vancouver

Hedegaard CJ, Krakauer M, Bendtzen K, Sørensen PS, Sellebjerg F, Nielsen CH. The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis. Clinical Immunology. 2008 okt. 1;129(1):80-9. https://doi.org/10.1016/j.clim.2008.06.007, https://doi.org/10.1016/j.clim.2008.06.007

Author

Hedegaard, Chris J ; Krakauer, Martin ; Bendtzen, Klaus ; Sørensen, Per Soelberg ; Sellebjerg, Finn ; Nielsen, Claus H. / The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis. I: Clinical Immunology. 2008 ; Bind 129, Nr. 1. s. 80-9.

Bibtex

@article{760a0660f37311ddbf70000ea68e967b,

title = "The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis",

abstract = "Interferon (IFN)-beta therapy has well-established clinical benefits in multiple sclerosis (MS), but the underlying modulation of cytokine responses to myelin self-antigens remains poorly understood. We analysed the CD4+ T cell proliferation and cytokine responses elicited by myelin basic protein (MBP) and a foreign recall antigen, tetanus toxoid (TT), in mononuclear cell cultures from fourteen MS patients undergoing IFN-beta therapy. The MBP-elicited IFN-gamma-, TNF-alpha- and IL-10 production decreased during therapy (p",

author = "Hedegaard, {Chris J} and Martin Krakauer and Klaus Bendtzen and S{\o}rensen, {Per Soelberg} and Finn Sellebjerg and Nielsen, {Claus H}",

year = "2008",

month = oct,

day = "1",

doi = "10.1016/j.clim.2008.06.007",

language = "English",

volume = "129",

pages = "80--9",

journal = "Clinical Immunology",

issn = "1521-6616",

publisher = "Academic Press",

number = "1",

}

RIS

TY - JOUR

T1 - The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

AU - Hedegaard, Chris J

AU - Krakauer, Martin

AU - Bendtzen, Klaus

AU - Sørensen, Per Soelberg

AU - Sellebjerg, Finn

AU - Nielsen, Claus H

PY - 2008/10/1

Y1 - 2008/10/1

N2 - Interferon (IFN)-beta therapy has well-established clinical benefits in multiple sclerosis (MS), but the underlying modulation of cytokine responses to myelin self-antigens remains poorly understood. We analysed the CD4+ T cell proliferation and cytokine responses elicited by myelin basic protein (MBP) and a foreign recall antigen, tetanus toxoid (TT), in mononuclear cell cultures from fourteen MS patients undergoing IFN-beta therapy. The MBP-elicited IFN-gamma-, TNF-alpha- and IL-10 production decreased during therapy (p

AB - Interferon (IFN)-beta therapy has well-established clinical benefits in multiple sclerosis (MS), but the underlying modulation of cytokine responses to myelin self-antigens remains poorly understood. We analysed the CD4+ T cell proliferation and cytokine responses elicited by myelin basic protein (MBP) and a foreign recall antigen, tetanus toxoid (TT), in mononuclear cell cultures from fourteen MS patients undergoing IFN-beta therapy. The MBP-elicited IFN-gamma-, TNF-alpha- and IL-10 production decreased during therapy (p

U2 - 10.1016/j.clim.2008.06.007

DO - 10.1016/j.clim.2008.06.007

M3 - Journal article

C2 - 18653385

VL - 129

SP - 80

EP - 89

JO - Clinical Immunology

JF - Clinical Immunology

SN - 1521-6616

IS - 1

ER -

ID: 10153154