Technical Considerations for Dynamic Myocardial Computed Tomography Perfusion as Part of a Comprehensive Evaluation of Coronary Artery Disease Using Computed Tomography

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

  • Mathias B. Møller
  • Joanne D. Schuijf
  • Noriko Oyama-Manabe
  • Jesper J. Linde
  • Jørgen T. Kühl
  • Joao A.C. Lima
  • Kofoed, Klaus Fuglsang

Dynamic myocardial computed tomography perfusion (DM-CTP) has good diagnostic accuracy for identifying myocardial ischemia as compared with both invasive and noninvasive reference standards. However, DM-CTP has not yet been implemented in the routine clinical examination of patients with suspected or known coronary artery disease. An important hurdle in the clinical dissemination of the method is the development of the DM-CTP acquisition protocol and image analysis. Therefore, the aim of this article is to provide a review of critical parameters in the design and execution of DM-CTP to optimize each step of the examination and avoid common mistakes. We aim to support potential users in the successful implementation and performance of DM-CTP in daily practice. When performed appropriately, DM-CTP may support clinical decision making. In addition, when combined with coronary computed tomography angiography, it has the potential to shorten the time to diagnosis by providing immediate visualization of both coronary atherosclerosis and its functional relevance using one single modality.

OriginalsprogEngelsk
TidsskriftJournal of Thoracic Imaging
Vol/bind38
Udgave nummer1
Sider (fra-til)54-68
Antal sider15
ISSN0883-5993
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
Mathias B. Møller has received grants from The Research Council of Rigshopitalet anm The Research Council of the Heart Center, Rigshospitalet. Joanne D. Schuijf is an employee of Canon Medical Systems Europe. Noriko Oyama-Manabe has received grants from, Canon Medical Systems Corporation, and from the Japan Society for the Promotion of Science (JSPS) KAKENHI # 26461780, has activities as a consultant for Canon Medical Systems, and received payment for lectures from Daiichi-Sankyo, Philips Medical Systems, Eisai, Bayer Healthcare, GE Healthcare, Nihon Medi-Physics Co. Ltd and Canon Medical Systems. Jørgen T. Kühl has received funding from the Research Council of Rigshospitalet. Jesper J. Linde has received grants from The Danish Research Foundation and The Research Council of Rigshospitalet. Klaus F. Kofoed AP Moller og hustru Chastine McKinney Mollers Fond, The John and Birthe Meyer Foundation, The Danish Agency for Science, Technology and Innovation, The Lundbeck Foundation, GE Healthcare, Canon Medical Systems, The Danish Heart Foundation, The University of Copenhagen, and is on the Speakers Bureau of Canon Medical Systems Corporation. The remaining authors declare no conflicts of interest.

Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.

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