Shot-noise limited, supercontinuum-based optical coherence tomography

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Shot-noise limited, supercontinuum-based optical coherence tomography. / Rao D. S, Shreesha; Jensen, Mikkel; Grüner-Nielsen, Lars; Olsen, Jesper Toft; Heiduschka, Peter; Kemper, Björn; Schnekenburger, Jürgen; Glud, Martin; Mogensen, Mette; Israelsen, Niels Møller; Bang, Ole.

I: Light: Science and Applications, Bind 10, Nr. 1, 133, 2021.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Rao D. S, S, Jensen, M, Grüner-Nielsen, L, Olsen, JT, Heiduschka, P, Kemper, B, Schnekenburger, J, Glud, M, Mogensen, M, Israelsen, NM & Bang, O 2021, 'Shot-noise limited, supercontinuum-based optical coherence tomography', Light: Science and Applications, bind 10, nr. 1, 133. https://doi.org/10.1038/s41377-021-00574-x

APA

Rao D. S, S., Jensen, M., Grüner-Nielsen, L., Olsen, J. T., Heiduschka, P., Kemper, B., Schnekenburger, J., Glud, M., Mogensen, M., Israelsen, N. M., & Bang, O. (2021). Shot-noise limited, supercontinuum-based optical coherence tomography. Light: Science and Applications, 10(1), [133]. https://doi.org/10.1038/s41377-021-00574-x

Vancouver

Rao D. S S, Jensen M, Grüner-Nielsen L, Olsen JT, Heiduschka P, Kemper B o.a. Shot-noise limited, supercontinuum-based optical coherence tomography. Light: Science and Applications. 2021;10(1). 133. https://doi.org/10.1038/s41377-021-00574-x

Author

Rao D. S, Shreesha ; Jensen, Mikkel ; Grüner-Nielsen, Lars ; Olsen, Jesper Toft ; Heiduschka, Peter ; Kemper, Björn ; Schnekenburger, Jürgen ; Glud, Martin ; Mogensen, Mette ; Israelsen, Niels Møller ; Bang, Ole. / Shot-noise limited, supercontinuum-based optical coherence tomography. I: Light: Science and Applications. 2021 ; Bind 10, Nr. 1.

Bibtex

@article{98b7c8fdc8da4a31b886783b332564dd,
title = "Shot-noise limited, supercontinuum-based optical coherence tomography",
abstract = "We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with an axial resolution of 5.9 μm at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-to-pulse relative intensity noise of the supercontinuum source. To overcome this disadvantage, we have developed a low-noise supercontinuum source based on an all-normal dispersion (ANDi) fiber, pumped by a femtosecond laser. The noise performance of our 90 MHz ANDi fiber-based supercontinuum source is compared to that of two commercial sources operating at 80 and 320 MHz repetition rate. We show that the low-noise of the ANDi fiber-based supercontinuum source improves the OCT images significantly in terms of both higher contrast, better sensitivity, and improved penetration. From SD-OCT imaging of skin, retina, and multilayer stacks we conclude that supercontinuum-based SD-OCT can enter the domain of shot-noise limited detection.",
author = "{Rao D. S}, Shreesha and Mikkel Jensen and Lars Gr{\"u}ner-Nielsen and Olsen, {Jesper Toft} and Peter Heiduschka and Bj{\"o}rn Kemper and J{\"u}rgen Schnekenburger and Martin Glud and Mette Mogensen and Israelsen, {Niels M{\o}ller} and Ole Bang",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
doi = "10.1038/s41377-021-00574-x",
language = "English",
volume = "10",
journal = "Light: Science and Applications",
issn = "2095-5545",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Shot-noise limited, supercontinuum-based optical coherence tomography

AU - Rao D. S, Shreesha

AU - Jensen, Mikkel

AU - Grüner-Nielsen, Lars

AU - Olsen, Jesper Toft

AU - Heiduschka, Peter

AU - Kemper, Björn

AU - Schnekenburger, Jürgen

AU - Glud, Martin

AU - Mogensen, Mette

AU - Israelsen, Niels Møller

AU - Bang, Ole

N1 - Publisher Copyright: © 2021, The Author(s).

PY - 2021

Y1 - 2021

N2 - We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with an axial resolution of 5.9 μm at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-to-pulse relative intensity noise of the supercontinuum source. To overcome this disadvantage, we have developed a low-noise supercontinuum source based on an all-normal dispersion (ANDi) fiber, pumped by a femtosecond laser. The noise performance of our 90 MHz ANDi fiber-based supercontinuum source is compared to that of two commercial sources operating at 80 and 320 MHz repetition rate. We show that the low-noise of the ANDi fiber-based supercontinuum source improves the OCT images significantly in terms of both higher contrast, better sensitivity, and improved penetration. From SD-OCT imaging of skin, retina, and multilayer stacks we conclude that supercontinuum-based SD-OCT can enter the domain of shot-noise limited detection.

AB - We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with an axial resolution of 5.9 μm at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-to-pulse relative intensity noise of the supercontinuum source. To overcome this disadvantage, we have developed a low-noise supercontinuum source based on an all-normal dispersion (ANDi) fiber, pumped by a femtosecond laser. The noise performance of our 90 MHz ANDi fiber-based supercontinuum source is compared to that of two commercial sources operating at 80 and 320 MHz repetition rate. We show that the low-noise of the ANDi fiber-based supercontinuum source improves the OCT images significantly in terms of both higher contrast, better sensitivity, and improved penetration. From SD-OCT imaging of skin, retina, and multilayer stacks we conclude that supercontinuum-based SD-OCT can enter the domain of shot-noise limited detection.

U2 - 10.1038/s41377-021-00574-x

DO - 10.1038/s41377-021-00574-x

M3 - Journal article

C2 - 34183643

AN - SCOPUS:85111141112

VL - 10

JO - Light: Science and Applications

JF - Light: Science and Applications

SN - 2095-5545

IS - 1

M1 - 133

ER -

ID: 302460257