Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models). Marked fine-scale heterogeneity of transmission has been observed in the field (i.e., over a few kilometres), but there are relatively few data on the degree of mixing. Since the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is highly polymorphic, the host's serological responses may be used to infer exposure to parasite sub-populations.
Originalsprog | Engelsk |
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Tidsskrift | P L o S One |
Vol/bind | 6 |
Udgave nummer | 6 |
Sider (fra-til) | e21711 |
ISSN | 1932-6203 |
DOI | |
Status | Udgivet - 1 jan. 2011 |
ID: 35277228