School performance from primary education in the adolescent offspring of parents with schizophrenia and bipolar disorder- a national, register-based study
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School performance from primary education in the adolescent offspring of parents with schizophrenia and bipolar disorder- a national, register-based study. / Ranning, Anne; Laursen, Thomas; Agerbo, Esben; Thorup, Anne; Hjorthøj, Carsten; Jepsen, Jens Richardt Møllegaard; Nordentoft, Merete.
I: Psychological Medicine, Bind 48, Nr. 12, 2018, s. 1993-2000.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - School performance from primary education in the adolescent offspring of parents with schizophrenia and bipolar disorder- a national, register-based study
AU - Ranning, Anne
AU - Laursen, Thomas
AU - Agerbo, Esben
AU - Thorup, Anne
AU - Hjorthøj, Carsten
AU - Jepsen, Jens Richardt Møllegaard
AU - Nordentoft, Merete
PY - 2018
Y1 - 2018
N2 - BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BP) are causes of severe disability worldwide and parents' severe mental illness (SMI) is associated with childhood adversity, and socio-emotional and cognitive problems in children. Yet, how parental BP and SZ affect educational attainment in offspring is still unclear.METHOD: We included all children (N = 684.248) born and living in Denmark between 1986 and 1996 and their parents. Our follow-up lasted from 1986 until children's graduation in 2014. The main outcome variable was their school grades following their primary education. School outcomes were divided into four categories: not graduated, low-grade point average (GPA), medium GPA and high GPA. We then performed a multiple logistic regression with medium GPA as the reference category, with the children of parents without SZ or BP as the reference group.RESULTS: Children of parents with SZ faced higher odds than their peers of not graduating primary education (OR 2.6), along with low GPA (odds ratios (OR) 1.6) and lower odds for a high GPA (OR 0.7). Moreover, it was the children of mothers rather than fathers with BP who had higher odds of not graduating primary education (OR 1.6). Lastly, child placement was associated with lower grades and lower graduation rates, and outcomes for children of parents with SMI were favorable compared with other children placed in care.CONCLUSION: For children, parental SZ is associated with lower grades and lower chances for graduating primary education. In contrast, the children of parents with BP were indistinguishable from the reference group regarding school grades. This signifies that specificity of parental severe mental illness is important in relation to educational achievement of children.
AB - BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BP) are causes of severe disability worldwide and parents' severe mental illness (SMI) is associated with childhood adversity, and socio-emotional and cognitive problems in children. Yet, how parental BP and SZ affect educational attainment in offspring is still unclear.METHOD: We included all children (N = 684.248) born and living in Denmark between 1986 and 1996 and their parents. Our follow-up lasted from 1986 until children's graduation in 2014. The main outcome variable was their school grades following their primary education. School outcomes were divided into four categories: not graduated, low-grade point average (GPA), medium GPA and high GPA. We then performed a multiple logistic regression with medium GPA as the reference category, with the children of parents without SZ or BP as the reference group.RESULTS: Children of parents with SZ faced higher odds than their peers of not graduating primary education (OR 2.6), along with low GPA (odds ratios (OR) 1.6) and lower odds for a high GPA (OR 0.7). Moreover, it was the children of mothers rather than fathers with BP who had higher odds of not graduating primary education (OR 1.6). Lastly, child placement was associated with lower grades and lower graduation rates, and outcomes for children of parents with SMI were favorable compared with other children placed in care.CONCLUSION: For children, parental SZ is associated with lower grades and lower chances for graduating primary education. In contrast, the children of parents with BP were indistinguishable from the reference group regarding school grades. This signifies that specificity of parental severe mental illness is important in relation to educational achievement of children.
U2 - 10.1017/S0033291717003518
DO - 10.1017/S0033291717003518
M3 - Journal article
C2 - 29239287
VL - 48
SP - 1993
EP - 2000
JO - Psychological Medicine
JF - Psychological Medicine
SN - 0033-2917
IS - 12
ER -
ID: 216570037