RNAcentral 2021: Secondary structure integration, improved sequence search and new member databases
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- RNAcentral 2021: secondary structure integration, improved sequence search and new member databases
Forlagets udgivne version, 2,1 MB, PDF-dokument
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that provides a single access point to 44 RNA resources and >18 million ncRNA sequences from a wide range of organisms and RNA types. RNAcentral now also includes secondary (2D) structure information for >13 million sequences, making RNAcentral the world's largest RNA 2D structure database. The 2D diagrams are displayed using R2DT, a new 2D structure visualization method that uses consistent, reproducible and recognizable layouts for related RNAs. The sequence similarity search has been updated with a faster interface featuring facets for filtering search results by RNA type, organism, source database or any keyword. This sequence search tool is available as a reusable web component, and has been integrated into several RNAcentral member databases, including Rfam, miRBase and snoDB. To allow for a more fine-grained assignment of RNA types and subtypes, all RNAcentral sequences have been annotated with Sequence Ontology terms. The RNAcentral database continues to grow and provide a central data resource for the RNA community. RNAcentral is freely available at https://rnacentral.org.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Nucleic Acids Research |
Vol/bind | 49 |
Udgave nummer | D1 |
Sider (fra-til) | D212-D220 |
ISSN | 0305-1048 |
DOI | |
Status | Udgivet - 2021 |
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