TY - JOUR

T1 - Recurrence rate and patient satisfaction of CO2 laser evaporation of lesions in patients with hidradenitis suppurativa

T2 - a retrospective study

AU - Mikkelsen, Peter Riis

AU - Dufour, Deirde Nathalie

AU - Zarchi, Kian

AU - Jemec, Gregor B E

PY - 2015/2

Y1 - 2015/2

N2 - BACKGROUND: Hidradenitis suppurativa (HS) is a debilitating disease and is difficult to treat. Validation of surgical techniques is therefore of great importance in the management of HS. Carbon dioxide (CO2) laser evaporation has been shown effective, but larger-scale studies are scarce.OBJECTIVE: To determine the recurrence rate, time to recurrence, and factors influencing disease recurrence in skin treated with CO2 laser evaporation, and healing by secondary intention; and patients' satisfaction with treatment.METHODS: Fifty-eight patients treated with CO2 laser evaporation were interviewed regarding recurrence and satisfaction after a mean of 25.7 months.RESULTS: Seventeen of 58 (29%) reported recurrence of HS lesions within the borders of the treated areas after a mean of 12.7 months. Obesity was a risk factor for recurrence with a hazard ratio of 4.53. Fifty-five patients (95%) reported some or great improvement, and 91% would recommend the CO2 laser surgery to other HS patients.CONCLUSION: This study supports the claim that CO2 laser treatment is an effective modality for recurrent HS lesions in a majority of patients. The authors identified obesity as a risk factor for recurrence. Self-reported satisfaction is high, and only 3 of 58 report no change in the condition. None reported a worsening.

AB - BACKGROUND: Hidradenitis suppurativa (HS) is a debilitating disease and is difficult to treat. Validation of surgical techniques is therefore of great importance in the management of HS. Carbon dioxide (CO2) laser evaporation has been shown effective, but larger-scale studies are scarce.OBJECTIVE: To determine the recurrence rate, time to recurrence, and factors influencing disease recurrence in skin treated with CO2 laser evaporation, and healing by secondary intention; and patients' satisfaction with treatment.METHODS: Fifty-eight patients treated with CO2 laser evaporation were interviewed regarding recurrence and satisfaction after a mean of 25.7 months.RESULTS: Seventeen of 58 (29%) reported recurrence of HS lesions within the borders of the treated areas after a mean of 12.7 months. Obesity was a risk factor for recurrence with a hazard ratio of 4.53. Fifty-five patients (95%) reported some or great improvement, and 91% would recommend the CO2 laser surgery to other HS patients.CONCLUSION: This study supports the claim that CO2 laser treatment is an effective modality for recurrent HS lesions in a majority of patients. The authors identified obesity as a risk factor for recurrence. Self-reported satisfaction is high, and only 3 of 58 report no change in the condition. None reported a worsening.

KW - Adult

KW - Female

KW - Follow-Up Studies

KW - Hidradenitis Suppurativa

KW - Humans

KW - Lasers, Gas

KW - Male

KW - Middle Aged

KW - Obesity

KW - Patient Satisfaction

KW - Recurrence

KW - Retrospective Studies

KW - Risk Factors

KW - Smoking

KW - Time Factors

KW - Journal Article

U2 - 10.1097/DSS.0000000000000264

DO - 10.1097/DSS.0000000000000264

M3 - Journal article

C2 - 25654196

VL - 41

SP - 255

EP - 260

JO - Dermatologic Surgery

JF - Dermatologic Surgery

SN - 1076-0512

IS - 2

ER -