Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

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Standard

Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105 : implications for visualizing cancer invasion. / Persson, Morten; Madsen, Jacob; Østergaard, Søren; Jensen, Mette Munk; Jørgensen, Jesper Tranekjær; Juhl, Karina; Lehmann, Charlotte; Ploug, Michael; Kjaer, Andreas.

I: Journal of Nuclear Medicine, Bind 53, Nr. 1, 2012, s. 138-45.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Persson, M, Madsen, J, Østergaard, S, Jensen, MM, Jørgensen, JT, Juhl, K, Lehmann, C, Ploug, M & Kjaer, A 2012, 'Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion', Journal of Nuclear Medicine, bind 53, nr. 1, s. 138-45. https://doi.org/10.2967/jnumed.110.083386

APA

Persson, M., Madsen, J., Østergaard, S., Jensen, M. M., Jørgensen, J. T., Juhl, K., Lehmann, C., Ploug, M., & Kjaer, A. (2012). Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion. Journal of Nuclear Medicine, 53(1), 138-45. https://doi.org/10.2967/jnumed.110.083386

Vancouver

Persson M, Madsen J, Østergaard S, Jensen MM, Jørgensen JT, Juhl K o.a. Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion. Journal of Nuclear Medicine. 2012;53(1):138-45. https://doi.org/10.2967/jnumed.110.083386

Author

Persson, Morten ; Madsen, Jacob ; Østergaard, Søren ; Jensen, Mette Munk ; Jørgensen, Jesper Tranekjær ; Juhl, Karina ; Lehmann, Charlotte ; Ploug, Michael ; Kjaer, Andreas. / Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105 : implications for visualizing cancer invasion. I: Journal of Nuclear Medicine. 2012 ; Bind 53, Nr. 1. s. 138-45.

Bibtex

@article{3af5063b747a438daa96d67ef6b3bc0d,
title = "Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion",
abstract = "Expression levels of the urokinase-type plasminogen activator receptor (uPAR) represent an established biomarker for poor prognosis in a variety of human cancers. The objective of the present study was to explore whether noninvasive PET can be used to perform a quantitative assessment of expression levels of uPAR across different human cancer xenograft models in mice and to illustrate the clinical potential of uPAR PET in future settings for individualized therapy.",
keywords = "Animals, Cell Transformation, Neoplastic, Colorectal Neoplasms, Copper Radioisotopes, Female, Gene Expression Regulation, Neoplastic, HT29 Cells, Heterocyclic Compounds, 1-Ring, Humans, Mice, Neoplasm Invasiveness, Oligopeptides, Positron-Emission Tomography, Positron-Emission Tomography and Computed Tomography, Radiochemistry, Receptors, Urokinase Plasminogen Activator",
author = "Morten Persson and Jacob Madsen and S{\o}ren {\O}stergaard and Jensen, {Mette Munk} and J{\o}rgensen, {Jesper Tranekj{\ae}r} and Karina Juhl and Charlotte Lehmann and Michael Ploug and Andreas Kjaer",
year = "2012",
doi = "10.2967/jnumed.110.083386",
language = "English",
volume = "53",
pages = "138--45",
journal = "The Journal of Nuclear Medicine",
issn = "0161-5505",
publisher = "Society of Nuclear Medicine",
number = "1",

}

RIS

TY - JOUR

T1 - Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105

T2 - implications for visualizing cancer invasion

AU - Persson, Morten

AU - Madsen, Jacob

AU - Østergaard, Søren

AU - Jensen, Mette Munk

AU - Jørgensen, Jesper Tranekjær

AU - Juhl, Karina

AU - Lehmann, Charlotte

AU - Ploug, Michael

AU - Kjaer, Andreas

PY - 2012

Y1 - 2012

N2 - Expression levels of the urokinase-type plasminogen activator receptor (uPAR) represent an established biomarker for poor prognosis in a variety of human cancers. The objective of the present study was to explore whether noninvasive PET can be used to perform a quantitative assessment of expression levels of uPAR across different human cancer xenograft models in mice and to illustrate the clinical potential of uPAR PET in future settings for individualized therapy.

AB - Expression levels of the urokinase-type plasminogen activator receptor (uPAR) represent an established biomarker for poor prognosis in a variety of human cancers. The objective of the present study was to explore whether noninvasive PET can be used to perform a quantitative assessment of expression levels of uPAR across different human cancer xenograft models in mice and to illustrate the clinical potential of uPAR PET in future settings for individualized therapy.

KW - Animals

KW - Cell Transformation, Neoplastic

KW - Colorectal Neoplasms

KW - Copper Radioisotopes

KW - Female

KW - Gene Expression Regulation, Neoplastic

KW - HT29 Cells

KW - Heterocyclic Compounds, 1-Ring

KW - Humans

KW - Mice

KW - Neoplasm Invasiveness

KW - Oligopeptides

KW - Positron-Emission Tomography

KW - Positron-Emission Tomography and Computed Tomography

KW - Radiochemistry

KW - Receptors, Urokinase Plasminogen Activator

U2 - 10.2967/jnumed.110.083386

DO - 10.2967/jnumed.110.083386

M3 - Journal article

C2 - 22213823

VL - 53

SP - 138

EP - 145

JO - The Journal of Nuclear Medicine

JF - The Journal of Nuclear Medicine

SN - 0161-5505

IS - 1

ER -

ID: 40215604