Persistence of contact allergy among Danish adults: an 8-year follow-up study
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Persistence of contact allergy among Danish adults : an 8-year follow-up study. / Nielsen, N H; Linneberg, A; Menné, T; Madsen, F; Frølund, L; Dirksen, A; Jørgensen, T.
I: Contact Dermatitis, Bind 45, Nr. 6, 12.2001, s. 350-3.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Persistence of contact allergy among Danish adults
T2 - an 8-year follow-up study
AU - Nielsen, N H
AU - Linneberg, A
AU - Menné, T
AU - Madsen, F
AU - Frølund, L
AU - Dirksen, A
AU - Jørgensen, T
PY - 2001/12
Y1 - 2001/12
N2 - In 1990, a random sample of 567 persons of the 15-69-year-old population living in the Western part of Copenhagen County, Denmark, was patch tested in a cross-sectional study. In 1998, a follow-up study was performed. Out of 540 invited, 365 (68%) were re-patch tested. In the follow-up study, the persistence of allergic contact sensitivity, defined as 1 or more positive patch tests in both surveys, was 71% (37 out of 52 subjects). Nickel allergy persisted in 79% (19 out of 24 subjects), while 60% (21 out of 35 subjects) had a positive patch test reaction to 1 or more allergens, other than nickel, in both surveys. The lowest persistence was 50% (5 out of 10 subjects) and this was found for patch test reactivity to 1 or more of the cosmetic ingredients included in the patch test series. 8 years after the baseline study had demonstrated allergic contact sensitivity, 71% of the subjects still had at least 1 positive patch test. Nickel allergy persisted in 79%. Allergen avoidance should probably be lifelong to prevent elicitation of contact dermatitis.
AB - In 1990, a random sample of 567 persons of the 15-69-year-old population living in the Western part of Copenhagen County, Denmark, was patch tested in a cross-sectional study. In 1998, a follow-up study was performed. Out of 540 invited, 365 (68%) were re-patch tested. In the follow-up study, the persistence of allergic contact sensitivity, defined as 1 or more positive patch tests in both surveys, was 71% (37 out of 52 subjects). Nickel allergy persisted in 79% (19 out of 24 subjects), while 60% (21 out of 35 subjects) had a positive patch test reaction to 1 or more allergens, other than nickel, in both surveys. The lowest persistence was 50% (5 out of 10 subjects) and this was found for patch test reactivity to 1 or more of the cosmetic ingredients included in the patch test series. 8 years after the baseline study had demonstrated allergic contact sensitivity, 71% of the subjects still had at least 1 positive patch test. Nickel allergy persisted in 79%. Allergen avoidance should probably be lifelong to prevent elicitation of contact dermatitis.
KW - Adolescent
KW - Adult
KW - Aged
KW - Allergens
KW - Cross-Sectional Studies
KW - Denmark
KW - Dermatitis, Allergic Contact
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Middle Aged
KW - Nickel
KW - Patch Tests
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
M3 - Journal article
C2 - 11846751
VL - 45
SP - 350
EP - 353
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 6
ER -
ID: 173164040