Parathyroideahormonrelateret peptid-induceret humoral hyperkalkæmi ved malignitet
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Parathyroideahormonrelateret peptid-induceret humoral hyperkalkæmi ved malignitet. / Tfelt-Hansen, Jacob; Brixen, Kim T.; Mosekilde, Leif; Schwarz, Peter.
I: Ugeskrift for Laeger, Bind 167, Nr. 8, 21.02.2005, s. 924-926.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Parathyroideahormonrelateret peptid-induceret humoral hyperkalkæmi ved malignitet
AU - Tfelt-Hansen, Jacob
AU - Brixen, Kim T.
AU - Mosekilde, Leif
AU - Schwarz, Peter
PY - 2005/2/21
Y1 - 2005/2/21
N2 - Humoral hypercalcaemia of malignancy (HHM) is defined by a tumor producing hypercalcemia through a systemic hormone or cytokine. In approximately 80% of HHM cases, parathyroid hormone-related peptide (PTHrP) is the causal factor. Primary hyperparathyroidism (PHPT) and metastasis to the bone are the most important differential diagnoses. The treatment strategy in cases of HHM is to decrease the serum calcium by fluid, loop diuretics, glucorticoids and bisphosphonate. Moreover, the underlying malignant disease should be treated. The prognosis for patients with HHM, however, is poor.
AB - Humoral hypercalcaemia of malignancy (HHM) is defined by a tumor producing hypercalcemia through a systemic hormone or cytokine. In approximately 80% of HHM cases, parathyroid hormone-related peptide (PTHrP) is the causal factor. Primary hyperparathyroidism (PHPT) and metastasis to the bone are the most important differential diagnoses. The treatment strategy in cases of HHM is to decrease the serum calcium by fluid, loop diuretics, glucorticoids and bisphosphonate. Moreover, the underlying malignant disease should be treated. The prognosis for patients with HHM, however, is poor.
UR - http://www.scopus.com/inward/record.url?scp=14844304289&partnerID=8YFLogxK
M3 - Review
C2 - 15789851
AN - SCOPUS:14844304289
VL - 167
SP - 924
EP - 926
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 8
ER -
ID: 203876739