Occupational type I allergy to christmas cactus (Schlumbergera)
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The study aimed to determine whether occupational contact urticaria and symptoms of mucous membranes, reported by five workers in a cactus nursery, were due to IgE-mediated allergy to Schlumbergera cacti. The five persons had positive skin prick tests to the plants as is and positive histamine- release tests, and in three of them specific IgE to the cacti could be demonstrated by Maxisorp RAST and immunoblotting. Four of the patients were atopic, and the fifth had a positive skin prick test to cat dander, indicating latent atopy. Skin prick tests with cacti were negative in most atopic volunteers, and all had negative histamine-release tests. The results suggest a true IgE-mediated allergy to the cacti, and both genetic predisposition and close contact with the plants at work seem to be important factors in the emergence of this new occupational allergy.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Allergy: European Journal of Allergy and Clinical Immunology |
| Vol/bind | 52 |
| Udgave nummer | 6 |
| Sider (fra-til) | 656-660 |
| Antal sider | 5 |
| ISSN | 0105-4538 |
| DOI | |
| Status | Udgivet - 1997 |
Bibliografisk note
Funding Information:
This work was supported by National Institutes of Health (NIH) Grants NS-40296 and MH-104536 to J.T.L. N.A.A.-S. was supported in part by NIH Predoctoral Training Grant T32-GM-007287. We thank Ellie Heckscher and Gerry Rubin for sharing fly lines. We also thank the Bloomington Drosophila Stock Center (Indiana University, Bloomington, IN; NIH Grant P40-OD-018537), the Drosophila Genome Resource Center (Indiana University, Bloomington, IN; NIH Grant 2P40-OD-010949-10A1), the TRiP Center at Harvard Medical School (Boston, MA; NIH/National Institute of General Medical Sciences Grant R01-GM-084947), the Developmental Studies Hybridoma Bank (University of Iowa, Iowa City, IA), and the Vienna Drosophila Resource Center (Vienna, Austria) for providing the strains used in this study. In addition, we thank the staff and students in the Cold Spring Harbor Laboratory Drosophila Neurobiology course and members of the Littleton laboratory for sharing resources and advice.
ID: 313374667