Treating schizophrenia requires both antipsychotic medication and psychosocial interventions. This review summarises the current knowledge in this area. A mixed treatment meta-analysis has recently concluded that family interventions, psychoeducation and cognitive behavioural therapy show the greatest effect in preventing relapse and reducing symptoms. These are included in the Danish OPUS treatment, but far from all patients receive these treatment options. This needs to be prioritised, if we want to ensure the best treatment for all patients suffering from schizophrenia.