No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
A possible mechanism underlying cardiovascular morbidity after major vascular surgery may be the perioperative ischaemia-reperfusion with excessive oxygen-derived free-radical production and increased levels of circulating inflammatory mediators. We examined the effect of melatonin infusion during surgery and oral melatonin treatment for 3 days after surgery on biochemical markers of oxidative and inflammatory stress.
Originalsprog | Engelsk |
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Tidsskrift | European Journal of Vascular and Endovascular Surgery |
Vol/bind | 40 |
Udgave nummer | 4 |
Sider (fra-til) | 461-7 |
Antal sider | 7 |
ISSN | 1078-5884 |
DOI | |
Status | Udgivet - 1 okt. 2010 |
ID: 34073024