New insights into the diagnosis of hidradenitis suppurativa: Clinical presentations and phenotypes
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New insights into the diagnosis of hidradenitis suppurativa : Clinical presentations and phenotypes. / van der Zee, Hessel H; Jemec, Gregor B E.
I: Journal of the American Academy of Dermatology, Bind 73, Nr. 5 Suppl 1, 11.2015, s. S23-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - New insights into the diagnosis of hidradenitis suppurativa
T2 - Clinical presentations and phenotypes
AU - van der Zee, Hessel H
AU - Jemec, Gregor B E
N1 - Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.
PY - 2015/11
Y1 - 2015/11
N2 - Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequently, diagnosis is made largely through clinical presentation of the condition. The use of several validated tools assists in confirming the diagnosis and the severity of the disease. In future investigations, the identification of phenotypes and clinical subtypes--taking into account genetic variants--will serve to identify subpopulations of patients who are responsive to particular therapies, thereby improving the overall therapeutic picture for patients with HS. There is a potential for personalized, tailored delivery of therapy in the HS setting.
AB - Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequently, diagnosis is made largely through clinical presentation of the condition. The use of several validated tools assists in confirming the diagnosis and the severity of the disease. In future investigations, the identification of phenotypes and clinical subtypes--taking into account genetic variants--will serve to identify subpopulations of patients who are responsive to particular therapies, thereby improving the overall therapeutic picture for patients with HS. There is a potential for personalized, tailored delivery of therapy in the HS setting.
KW - Adult
KW - Anti-Infective Agents
KW - Anti-Inflammatory Agents
KW - Biopsy, Needle
KW - Female
KW - Genetic Predisposition to Disease
KW - Hidradenitis Suppurativa
KW - Humans
KW - Immunohistochemistry
KW - Male
KW - Phenotype
KW - Sensitivity and Specificity
KW - Severity of Illness Index
KW - Treatment Outcome
KW - Young Adult
KW - Comparative Study
KW - Journal Article
KW - Review
U2 - 10.1016/j.jaad.2015.07.047
DO - 10.1016/j.jaad.2015.07.047
M3 - Journal article
C2 - 26470610
VL - 73
SP - S23-6
JO - American Academy of Dermatology. Journal
JF - American Academy of Dermatology. Journal
SN - 0190-9622
IS - 5 Suppl 1
ER -
ID: 179171766