n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys
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n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys. / Damsgaard, Camilla Trab; Stark, Ken D; Hjorth, Mads Fiil; Biltoft-Jensen, Anja; Astrup, Arne; Michaelsen, Kim F; Lauritzen, Lotte.
I: British Journal of Nutrition, Bind 110, Nr. 7, 2013, s. 1304-1312.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys
AU - Damsgaard, Camilla Trab
AU - Stark, Ken D
AU - Hjorth, Mads Fiil
AU - Biltoft-Jensen, Anja
AU - Astrup, Arne
AU - Michaelsen, Kim F
AU - Lauritzen, Lotte
N1 - CURIS 2013 NEXS 079
PY - 2013
Y1 - 2013
N2 - Dietary n-3 long-chain PUFA (LC-PUFA) improve dyslipidaemia and hypertension and may affect insulin resistance and adiposity. Increasing numbers of children show signs of the metabolic syndrome (MetS), but few studies have investigated the association with n-3 LC-PUFA status. We examined the relationship between fasting whole-blood EPA or DHA (w/w% of the total fatty acids, FA%) and markers of the MetS (anthropometry, blood pressure, plasma lipids and glucose homeostasis) cross-sectionally in seventy-three 8-11-year-old Danish children from the OPUS School Meal Pilot Study (OPUS is an acronym of the project 'Optimal well-being, development and health for Danish children through a healthy New Nordic Diet' and is supported by a grant from the Nordea Foundation). Also, we explored the potential mediating effects of physical activity and energy intake. Girls had higher body fat percentage (BF%), diastolic blood pressure, heart rate, plasma TAG, insulin, homeostasis model assessment-insulin resistance and glycosylated Hb than boys. Sexes did not differ in fish or macronutrient intake or whole-blood fatty acids. After adjustment for sex, age and total whole-blood fatty acid concentration, BF% and HDL:TAG increased with whole-blood EPA (ß>0·25, P
AB - Dietary n-3 long-chain PUFA (LC-PUFA) improve dyslipidaemia and hypertension and may affect insulin resistance and adiposity. Increasing numbers of children show signs of the metabolic syndrome (MetS), but few studies have investigated the association with n-3 LC-PUFA status. We examined the relationship between fasting whole-blood EPA or DHA (w/w% of the total fatty acids, FA%) and markers of the MetS (anthropometry, blood pressure, plasma lipids and glucose homeostasis) cross-sectionally in seventy-three 8-11-year-old Danish children from the OPUS School Meal Pilot Study (OPUS is an acronym of the project 'Optimal well-being, development and health for Danish children through a healthy New Nordic Diet' and is supported by a grant from the Nordea Foundation). Also, we explored the potential mediating effects of physical activity and energy intake. Girls had higher body fat percentage (BF%), diastolic blood pressure, heart rate, plasma TAG, insulin, homeostasis model assessment-insulin resistance and glycosylated Hb than boys. Sexes did not differ in fish or macronutrient intake or whole-blood fatty acids. After adjustment for sex, age and total whole-blood fatty acid concentration, BF% and HDL:TAG increased with whole-blood EPA (ß>0·25, P
U2 - 10.1017/S0007114513000585
DO - 10.1017/S0007114513000585
M3 - Journal article
C2 - 23591057
VL - 110
SP - 1304
EP - 1312
JO - British Journal of Nutrition
JF - British Journal of Nutrition
SN - 0007-1145
IS - 7
ER -
ID: 45250000