Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts

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Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts. / Hvidtfeldt, Ulla Arthur; Chen, Jie; Rodopoulou, Sophia; Strak, Maciej; de Hoogh, Kees; Andersen, Zorana J; Bellander, Tom; Brandt, Jørgen; Forastiere, Francesco; Brynedal, Boel; Hertel, Ole; Hoffmann, Barbara; Katsouyanni, Klea; Ketzel, Matthias; Leander, Karin; Magnusson, Patrik K E; Nagel, Gabriele; Pershagen, Göran; Rizzuto, Debora; Samoli, Evangelia; So, Rina; Stafoggia, Massimo; Tjønneland, Anne; Weinmayr, Gudrun; Wolf, Kathrin; Zitt, Emanuel; Brunekreef, Bert; Hoek, Gerard; Raaschou-Nielsen, Ole.

I: Environmental Research, Bind 239, Nr. Pt 1, 117230, 2023.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hvidtfeldt, UA, Chen, J, Rodopoulou, S, Strak, M, de Hoogh, K, Andersen, ZJ, Bellander, T, Brandt, J, Forastiere, F, Brynedal, B, Hertel, O, Hoffmann, B, Katsouyanni, K, Ketzel, M, Leander, K, Magnusson, PKE, Nagel, G, Pershagen, G, Rizzuto, D, Samoli, E, So, R, Stafoggia, M, Tjønneland, A, Weinmayr, G, Wolf, K, Zitt, E, Brunekreef, B, Hoek, G & Raaschou-Nielsen, O 2023, 'Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts', Environmental Research, bind 239, nr. Pt 1, 117230. https://doi.org/10.1016/j.envres.2023.117230

APA

Hvidtfeldt, U. A., Chen, J., Rodopoulou, S., Strak, M., de Hoogh, K., Andersen, Z. J., Bellander, T., Brandt, J., Forastiere, F., Brynedal, B., Hertel, O., Hoffmann, B., Katsouyanni, K., Ketzel, M., Leander, K., Magnusson, P. K. E., Nagel, G., Pershagen, G., Rizzuto, D., ... Raaschou-Nielsen, O. (2023). Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts. Environmental Research, 239(Pt 1), [117230]. https://doi.org/10.1016/j.envres.2023.117230

Vancouver

Hvidtfeldt UA, Chen J, Rodopoulou S, Strak M, de Hoogh K, Andersen ZJ o.a. Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts. Environmental Research. 2023;239(Pt 1). 117230. https://doi.org/10.1016/j.envres.2023.117230

Author

Hvidtfeldt, Ulla Arthur ; Chen, Jie ; Rodopoulou, Sophia ; Strak, Maciej ; de Hoogh, Kees ; Andersen, Zorana J ; Bellander, Tom ; Brandt, Jørgen ; Forastiere, Francesco ; Brynedal, Boel ; Hertel, Ole ; Hoffmann, Barbara ; Katsouyanni, Klea ; Ketzel, Matthias ; Leander, Karin ; Magnusson, Patrik K E ; Nagel, Gabriele ; Pershagen, Göran ; Rizzuto, Debora ; Samoli, Evangelia ; So, Rina ; Stafoggia, Massimo ; Tjønneland, Anne ; Weinmayr, Gudrun ; Wolf, Kathrin ; Zitt, Emanuel ; Brunekreef, Bert ; Hoek, Gerard ; Raaschou-Nielsen, Ole. / Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts. I: Environmental Research. 2023 ; Bind 239, Nr. Pt 1.

Bibtex

@article{cea385a64bea4a08bb7568963d14e983,

title = "Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts",

abstract = "BACKGROUND: Air pollution is a growing concern worldwide, with significant impacts on human health. Multiple myeloma is a type of blood cancer with increasing incidence. Studies have linked air pollution exposure to various types of cancer, including leukemia and lymphoma, however, the relationship with multiple myeloma incidence has not been extensively investigated.METHODS: We pooled four European cohorts (N = 234,803) and assessed the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), and ozone (O3) and multiple myeloma. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level.RESULTS: During 4,415,817 person-years of follow-up (average 18.8 years), we observed 404 cases of multiple myeloma. The results of the fully adjusted linear analyses showed hazard ratios (95% confidence interval) of 0.99 (0.84, 1.16) per 10 μg/m³ NO2, 1.04 (0.82, 1.33) per 5 μg/m³ PM2.5, 0.99 (0.84, 1.18) per 0.5 10-5 m-1 BCE, and 1.11 (0.87, 1.41) per 10 μg/m³ O3.CONCLUSIONS: We did not observe an association between long-term ambient air pollution exposure and incidence of multiple myeloma.",

keywords = "Humans, Air Pollutants/toxicity, Air Pollution/adverse effects, Cohort Studies, Environmental Exposure/adverse effects, Multiple Myeloma/chemically induced, Nitrogen Dioxide/toxicity, Particulate Matter/analysis",

author = "Hvidtfeldt, {Ulla Arthur} and Jie Chen and Sophia Rodopoulou and Maciej Strak and {de Hoogh}, Kees and Andersen, {Zorana J} and Tom Bellander and J{\o}rgen Brandt and Francesco Forastiere and Boel Brynedal and Ole Hertel and Barbara Hoffmann and Klea Katsouyanni and Matthias Ketzel and Karin Leander and Magnusson, {Patrik K E} and Gabriele Nagel and G{\"o}ran Pershagen and Debora Rizzuto and Evangelia Samoli and Rina So and Massimo Stafoggia and Anne Tj{\o}nneland and Gudrun Weinmayr and Kathrin Wolf and Emanuel Zitt and Bert Brunekreef and Gerard Hoek and Ole Raaschou-Nielsen",

year = "2023",

doi = "10.1016/j.envres.2023.117230",

language = "English",

volume = "239",

journal = "Environmental Research",

issn = "0013-9351",

publisher = "Academic Press",

number = "Pt 1",

}

RIS

TY - JOUR

T1 - Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts

AU - Hvidtfeldt, Ulla Arthur

AU - Chen, Jie

AU - Rodopoulou, Sophia

AU - Strak, Maciej

AU - de Hoogh, Kees

AU - Andersen, Zorana J

AU - Bellander, Tom

AU - Brandt, Jørgen

AU - Forastiere, Francesco

AU - Brynedal, Boel

AU - Hertel, Ole

AU - Hoffmann, Barbara

AU - Katsouyanni, Klea

AU - Ketzel, Matthias

AU - Leander, Karin

AU - Magnusson, Patrik K E

AU - Nagel, Gabriele

AU - Pershagen, Göran

AU - Rizzuto, Debora

AU - Samoli, Evangelia

AU - So, Rina

AU - Stafoggia, Massimo

AU - Tjønneland, Anne

AU - Weinmayr, Gudrun

AU - Wolf, Kathrin

AU - Zitt, Emanuel

AU - Brunekreef, Bert

AU - Hoek, Gerard

AU - Raaschou-Nielsen, Ole

PY - 2023

Y1 - 2023

N2 - BACKGROUND: Air pollution is a growing concern worldwide, with significant impacts on human health. Multiple myeloma is a type of blood cancer with increasing incidence. Studies have linked air pollution exposure to various types of cancer, including leukemia and lymphoma, however, the relationship with multiple myeloma incidence has not been extensively investigated.METHODS: We pooled four European cohorts (N = 234,803) and assessed the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), and ozone (O3) and multiple myeloma. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level.RESULTS: During 4,415,817 person-years of follow-up (average 18.8 years), we observed 404 cases of multiple myeloma. The results of the fully adjusted linear analyses showed hazard ratios (95% confidence interval) of 0.99 (0.84, 1.16) per 10 μg/m³ NO2, 1.04 (0.82, 1.33) per 5 μg/m³ PM2.5, 0.99 (0.84, 1.18) per 0.5 10-5 m-1 BCE, and 1.11 (0.87, 1.41) per 10 μg/m³ O3.CONCLUSIONS: We did not observe an association between long-term ambient air pollution exposure and incidence of multiple myeloma.

AB - BACKGROUND: Air pollution is a growing concern worldwide, with significant impacts on human health. Multiple myeloma is a type of blood cancer with increasing incidence. Studies have linked air pollution exposure to various types of cancer, including leukemia and lymphoma, however, the relationship with multiple myeloma incidence has not been extensively investigated.METHODS: We pooled four European cohorts (N = 234,803) and assessed the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), and ozone (O3) and multiple myeloma. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level.RESULTS: During 4,415,817 person-years of follow-up (average 18.8 years), we observed 404 cases of multiple myeloma. The results of the fully adjusted linear analyses showed hazard ratios (95% confidence interval) of 0.99 (0.84, 1.16) per 10 μg/m³ NO2, 1.04 (0.82, 1.33) per 5 μg/m³ PM2.5, 0.99 (0.84, 1.18) per 0.5 10-5 m-1 BCE, and 1.11 (0.87, 1.41) per 10 μg/m³ O3.CONCLUSIONS: We did not observe an association between long-term ambient air pollution exposure and incidence of multiple myeloma.

KW - Humans

KW - Air Pollutants/toxicity

KW - Air Pollution/adverse effects

KW - Cohort Studies

KW - Environmental Exposure/adverse effects

KW - Multiple Myeloma/chemically induced

KW - Nitrogen Dioxide/toxicity

KW - Particulate Matter/analysis

U2 - 10.1016/j.envres.2023.117230

DO - 10.1016/j.envres.2023.117230

M3 - Journal article

C2 - 37806476

VL - 239

JO - Environmental Research

JF - Environmental Research

SN - 0013-9351

IS - Pt 1

M1 - 117230

ER -

ID: 374390047